Characterization of milk oligosaccharide and sialic acid content and their influence on brain sialic acid in a lean mouse model for gestational diabetes

F Liu, AJC Tol, F Kuipers, MH Oosterveer… - Heliyon, 2024 - cell.com
Oligosaccharides and sialic acids (Sia) are bioactive components in milk that contribute to
newborn development and health. Hyperglycemia in pregnancy (HIP) can have adverse …

Postpartum development of metabolic dysfunction-associated steatotic liver disease in a lean mouse model of gestational diabetes mellitus

K Hribar, D Eichhorn, L Bongiovanni, MH Koster… - Scientific Reports, 2024 - nature.com
Gestational diabetes mellitus (GDM) is associated with increased postpartum risk for
metabolic dysfunction-associated steatotic liver disease (MASLD). GDM-related MASLD …

Xylooligosaccharides ameliorate insulin resistance by increasing Akkermansia muciniphila and improving intestinal barrier dysfunction in gestational diabetes mellitus …

J Yang, J Wang, W Wu, C Su, Y Wu, Q Li - Food & Function, 2024 - pubs.rsc.org
Little is known regarding the effects of xylooligosaccharides (XOS) on insulin resistance (IR)
in gestational diabetes mellitus (GDM). We aimed to investigate this issue and its …

Two‐hits, two‐goals: An improved model for gestational diabetes mellitus and a novel link to the development of non‐alcoholic fatty liver disease.

NM Notaro, JM Budd - Journal of Physiology, 2023 - search.ebscohost.com
On GD18, a subset of GDM and PDM animals making up the pregnancy cohort were
euthanized for the analysis of pregnancy outcomes and maternal health. Keywords …

Omega-3 fatty acids prevent gestational diabetes mellitus via modulation of lipid metabolism

X Zhang, F Li, B Yang, W Zhang, Y Wang - Open Life Sciences, 2024 - degruyter.com
The incidence rate of gestational diabetes mellitus (GDM) remains high among pregnant
women in the second trimester of pregnancy. However, the main clinical approach to …

Hyperglycaemia in pregnancy: characterization, mitigation and implications for maternal and offspring health

K Hribar - 2024 - research.rug.nl
This thesis investigates the pathophysiology of lean gestational diabetes mellitus (GDM) and
its consequences for both mother and offspring. We use an innovative mouse model …