Melatonin: an ancient molecule that makes oxygen metabolically tolerable
Melatonin is remarkably functionally diverse with actions as a free radical scavenger and
antioxidant, circadian rhythm regulator, anti‐inflammatory and immunoregulating molecule …
antioxidant, circadian rhythm regulator, anti‐inflammatory and immunoregulating molecule …
Melatonin and its metabolites vs oxidative stress: From individual actions to collective protection
Oxidative stress (OS) represents a threat to the chemical integrity of biomolecules including
lipids, proteins, and DNA. The associated molecular damage frequently results in serious …
lipids, proteins, and DNA. The associated molecular damage frequently results in serious …
Melatonin: a well‐documented antioxidant with conditional pro‐oxidant actions
HM Zhang, Y Zhang - Journal of pineal research, 2014 - Wiley Online Library
Abstract Melatonin (N‐acetyl‐5‐methoxytryptamine), an indoleamine produced in many
organs including the pineal gland, was initially characterized as a hormone primarily …
organs including the pineal gland, was initially characterized as a hormone primarily …
Melatonin as a natural ally against oxidative stress: a physicochemical examination
Oxidative stress has been proven to be related to the onset of a large number of health
disorders. This chemical stress is triggered by an excess of free radicals, which are …
disorders. This chemical stress is triggered by an excess of free radicals, which are …
[HTML][HTML] Roles of melatonin in the field of reproductive medicine
W Yong, H Ma, M Na, T Gao, Y Zhang, L Hao… - Biomedicine & …, 2021 - Elsevier
Melatonin, mostly released by the pineal gland, is a circadian rhythm-regulated and
multifunctional hormone. Great advances in melatonin research have been made, including …
multifunctional hormone. Great advances in melatonin research have been made, including …
[HTML][HTML] Antioxidant therapies in traumatic brain and spinal cord injury
M Bains, ED Hall - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2012 - Elsevier
Free radical formation and oxidative damage have been extensively investigated and
validated as important contributors to the pathophysiology of acute central nervous system …
validated as important contributors to the pathophysiology of acute central nervous system …
One molecule, many derivatives: a never‐ending interaction of melatonin with reactive oxygen and nitrogen species?
DX Tan, LC Manchester, MP Terron… - Journal of pineal …, 2007 - Wiley Online Library
Melatonin is a highly conserved molecule. Its presence can be traced back to ancient
photosynthetic prokaryotes. A primitive and primary function of melatonin is that it acts as a …
photosynthetic prokaryotes. A primitive and primary function of melatonin is that it acts as a …
Actions of melatonin in the reduction of oxidative stress: a review
Melatonin was discovered to be a direct free radical scavenger less than 10 years ago.
Besides its ability to directly neutralize a number of free radicals and reactive oxygen and …
Besides its ability to directly neutralize a number of free radicals and reactive oxygen and …
Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger
Melatonin was found to be a potent free radical scavenger in 1993. Since then over 800
publications have directly or indirectly confirmed this observation. Melatonin scavenges a …
publications have directly or indirectly confirmed this observation. Melatonin scavenges a …
[图书][B] Oxidation and antioxidants in organic chemistry and biology
ET Denisov, IB Afanas' ev - 2005 - taylorfrancis.com
Providing a comprehensive review of reactions of oxidation for different classes of organic
compounds and polymers, and biological processes mediated by free radicals, Oxidation …
compounds and polymers, and biological processes mediated by free radicals, Oxidation …