Clonal haematopoiesis, ageing and kidney disease

C Vlasschaert, MB Lanktree, MJ Rauh… - Nature Reviews …, 2024 - nature.com
Clonal haematopoiesis of indeterminate potential (CHIP) is a preclinical condition wherein a
sizeable proportion of an individual's circulating blood cells are derived from a single …

Solid Organ Transplant Recipients Exhibit More TET2-Mutant Clonal Hematopoiesis of Indeterminate Potential Not Driven by Increased Transplantation Risk

AJ Silver, C Vlasschaert, T Mack, B Sharber, Y Xu… - Clinical Cancer …, 2024 - AACR
Purpose: Solid organ transplant recipients comprise a unique population of
immunosuppressed patients with increased risk of malignancy, including hematologic …

Molecular and clinical aspects relevant for counseling individuals with clonal hematopoiesis of indeterminate potential

AM Cacic, FI Schulz, U Germing, S Dietrich… - Frontiers in …, 2023 - frontiersin.org
Clonal hematopoiesis of indeterminate potential (CHIP) has fascinated the medical
community for some time. Discovered about a decade ago, this phenomenon links age …

Aging, Inflammation, and Comorbidity in Cancers—A General In Silico Study Exemplified by Myeloproliferative Malignancies

JT Ottesen, M Andersen - Cancers, 2023 - mdpi.com
Simple Summary Cancer escape links to the insufficient immune response. Thus, transition
from a pre-cancerous state to cancerous development induced by morbidities competing for …

Clonal hematopoiesis and inflammation in the vasculature: CHIVE, a prospective, longitudinal clonal hematopoiesis cohort and biorepository

ML Shannon, JB Heimlich, S Olson, A Debevec… - Blood …, 2024 - ashpublications.org
Clonal hematopoiesis (CH) is an age-associated phenomenon leading to an increased risk
of both hematologic malignancy and nonmalignant organ dysfunction. Increasingly available …

Clonal Hematopoiesis and Inflammation in the VasculaturE (CHIVE): a prospective, longitudinal clonal hematopoiesis cohort and biorepository

ML Shannon, JB Heimlich, S Olson, A Debevec… - Blood Advances, 2024 - Elsevier
Clonal hematopoiesis (CH) is an age-associated phenomenon leading to increased risk of
both hematologic malignancy and non-malignant organ dysfunction. Increasingly available …

Clonal Hematopoiesis of Indeterminate Potential and Long-term Outcomes in Heart Transplantation

P Simitsis, A Nohria, J Kelleher, J Boulet… - Journal of Cardiac …, 2024 - Elsevier
Background Clonal hematopoiesis of indeterminate potential (CHIP) mutations, a trait of
aging, has been associated with the progression of cardiovascular disease and the …

Clonal hematopoiesis of indeterminate potential is associated with reduced risk of cognitive impairment in patients with chronic kidney disease

C Xiao, MK Tamura, Y Pan, V Rao… - Alzheimer's & … - Wiley Online Library
INTRODUCTION Clonal hematopoiesis of indeterminate potential (CHIP) and dementia
disproportionately burden patients with chronic kidney disease (CKD). The association …

[PDF][PDF] Pre-MDS states: CHIP, CCUS, ICUS–How to manage in the clinic?

MR Savona - 2023 - mds-foundation.org
Clonal Hematopoiesis and Inflammation in the VasculaturE (CHIVE) CH Repository Cooperation
– Where we are in 2023 Page 1 Pre-MDS states: CHIP, CCUS, ICUS – How to manage in the …