Current understanding of the anatomy, physiology, and magnetic resonance imaging of neurofluids: update from the 2022 “ISMRM Imaging Neurofluids Study group” …

N Agarwal, LD Lewis, L Hirschler… - Journal of magnetic …, 2024 - Wiley Online Library
Neurofluids is a term introduced to define all fluids in the brain and spine such as blood,
cerebrospinal fluid, and interstitial fluid. Neuroscientists in the past millennium have steadily …

Glymphatic-lymphatic coupling: assessment of the evidence from magnetic resonance imaging of humans

G Ringstad, PK Eide - Cellular and Molecular Life Sciences, 2024 - Springer
The discoveries that cerebrospinal fluid participates in metabolic perivascular exchange with
the brain and further drains solutes to meningeal lymphatic vessels have sparked a …

Molecular trans-dural efflux to skull bone marrow in humans with CSF disorders

G Ringstad, PK Eide - Brain, 2022 - academic.oup.com
Dural sinuses were recently identified as a hub for peripheral immune surveillance of brain-
derived antigens cleared through CSF. However, animal studies have also indicated that …

[HTML][HTML] Clinical application of intrathecal gadobutrol for assessment of cerebrospinal fluid tracer clearance to blood

PK Eide, E Mariussen, H Uggerud, AH Pripp… - JCI insight, 2021 - ncbi.nlm.nih.gov
BACKGROUND Methodology for estimation of cerebrospinal fluid (CSF) tracer clearance
could have wide clinical application in predicting excretion of intrathecal drugs and …

Direction and magnitude of cerebrospinal fluid flow vary substantially across central nervous system diseases

PK Eide, LM Valnes, EK Lindstrøm, KA Mardal… - Fluids and Barriers of …, 2021 - Springer
Background Several central nervous system diseases are associated with disturbed
cerebrospinal fluid (CSF) flow patterns and have typically been characterized in vivo by …

Prospective T1 mapping to assess gadolinium retention in brain after intrathecal gadobutrol

G Ringstad, LM Valnes, SAS Vatnehol, AH Pripp… - Neuroradiology, 2023 - Springer
Purpose A possible pathway behind gadolinium retention in brain is leakage of contrast
agents from blood to cerebrospinal fluid and entry into brain along perivascular (glymphatic) …

Intrathecal contrast-enhanced magnetic resonance imaging of cerebrospinal fluid dynamics and glymphatic enhancement in idiopathic normal pressure …

PK Eide, A Lashkarivand, ÅA Hagen-Kersten… - Frontiers in …, 2022 - frontiersin.org
Idiopathic normal pressure hydrocephalus (iNPH) is a neurodegenerative disease,
characterized by cerebrospinal fluid (CSF) flow disturbance. Today, the only available …

Prospective safety study of intrathecal gadobutrol in different doses

A Sperre, I Karsrud, AHS Rodum… - American Journal …, 2023 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: In our clinical practice, we increasingly use intrathecal
contrast-enhanced glymphatic MR imaging to assess CSF disturbances. However, because …

Mechanisms behind changes of neurodegeneration biomarkers in plasma induced by sleep deprivation

PK Eide, A Lashkarivand, AH Pripp… - Brain …, 2023 - academic.oup.com
Acute sleep deprivation has been shown to affect cerebrospinal fluid and plasma
concentrations of biomarkers associated with neurodegeneration, though the mechanistic …

Cerebrospinal fluid production and absorption and ventricular enlargement mechanisms in hydrocephalus

S Yamada, M Mase - Neurologia medico-chirurgica, 2023 - jstage.jst.go.jp
Cerebrospinal fluid (CSF) production and absorption concept significantly changed in the
early 2010s from “third circulation theory” and “classical bulk flow theory” to a whole new …