Cellular senescence, classically defined as stable cell cycle arrest, is implicated in biological
processes such as embryogenesis, wound healing and ageing. Senescent cells have a …

Mesenchymal stem cells (MSCs) have been extensively investigated for the treatment of
various diseases. The therapeutic potential of MSCs is attributed to complex cellular and …

Human mesenchymal stem cells (MSCs) are primary multipotent cells capable of
differentiating into osteocytes, chondrocytes, and adipocytes when stimulated under …

Aging impairs the functions of human mesenchymal stem cells (MSCs), thereby severely
reducing their beneficial effects on myocardial infarction (MI). MicroRNAs (miRNAs) play …

Mesenchymal stem cell‐(MSC‐) based therapy is a novel strategy in regenerative medicine.
The functional and regenerative capacities of MSCs decline with senescence. Nonetheless …

In cell transplantation therapy, mesenchymal stem cells (MSCs) are ideal seed cells due to
their easy acquisition and cultivation, strong regenerative capacity, multi-directional …

The beneficial functions of mesenchymal stem cells (MSCs) decline with age, limiting their
therapeutic efficacy for myocardial infarction (MI). Macrophage migration inhibitory factor …

Background Idiopathic pulmonary fibrosis (IPF) is an age-related disease with no cure.
Mesenchymal stem cell (MSC)-based therapy has emerged as a novel strategy for IPF …

Mitochondrial dysfunction in neurons has been implicated in hypoxia-ischemia-induced
brain injury. Although mesenchymal stem cell therapy has emerged as a novel treatment for …

Mesenchymal stem/stromal cells (MSCs) have various properties that make them promising
candidates for stem cell-based therapies in clinical settings. These include self-renewal …