Unsupervised multi-omics data integration methods: a comprehensive review

N Vahabi, G Michailidis - Frontiers in genetics, 2022 - frontiersin.org
Through the developments of Omics technologies and dissemination of large-scale
datasets, such as those from The Cancer Genome Atlas, Alzheimer's Disease Neuroimaging …

Integrative methods and practical challenges for single-cell multi-omics

A Ma, A McDermaid, J Xu, Y Chang, Q Ma - Trends in biotechnology, 2020 - cell.com
Fast-developing single-cell multimodal omics (scMulti-omics) technologies enable the
measurement of multiple modalities, such as DNA methylation, chromatin accessibility, RNA …

Survey on multi-omics, and multi-omics data analysis, integration and application

MH Shahrajabian, W Sun - Current Pharmaceutical Analysis, 2023 - benthamdirect.com
Multi-omics approaches have developed as a profitable technique for plant systems, a
popular method in medical and biological sciences underlining the necessity to outline new …

OmicsAnalyst: a comprehensive web-based platform for visual analytics of multi-omics data

G Zhou, J Ewald, J Xia - Nucleic Acids Research, 2021 - academic.oup.com
Data analysis and interpretation remain a critical bottleneck in current multi-omics studies.
Here, we introduce OmicsAnalyst, a user-friendly, web-based platform that allows users to …

Computational oncology in the multi-omics era: state of the art

G de Anda-Jáuregui, E Hernández-Lemus - Frontiers in oncology, 2020 - frontiersin.org
Cancer is the quintessential complex disease. As technologies evolve faster each day, we
are able to quantify the different layers of biological elements that contribute to the …

Multi-omics model applied to cancer genetics

F Pettini, A Visibelli, V Cicaloni, D Iovinelli… - International journal of …, 2021 - mdpi.com
In this review, we focus on bioinformatic oncology as an integrative discipline that
incorporates knowledge from the mathematical, physical, and computational fields to further …

[HTML][HTML] Systems metabolomics: From metabolomic snapshots to design principles

C Damiani, D Gaglio, E Sacco, L Alberghina… - Current opinion in …, 2020 - Elsevier
Highlights•High content and physiological readouts allow precise definition of the system-
level metabolic state of cells or tissues.•Constraint-based metabolic models provide a …

An overview of technologies for MS-based proteomics-centric multi-omics

AT Rajczewski, PD Jagtap, TJ Griffin - Expert review of proteomics, 2022 - Taylor & Francis
Introduction Mass spectrometry-based proteomics reveals dynamic molecular signatures
underlying phenotypes reflecting normal and perturbed conditions in living systems …

Integrative network fusion: a multi-omics approach in molecular profiling

M Chierici, N Bussola, A Marcolini… - Frontiers in …, 2020 - frontiersin.org
Recent technological advances and international efforts, such as The Cancer Genome Atlas
(TCGA), have made available several pan-cancer datasets encompassing multiple omics …

Single sample pathway analysis in metabolomics: performance evaluation and application

C Wieder, RPJ Lai, TMD Ebbels - BMC bioinformatics, 2022 - Springer
Background Single sample pathway analysis (ssPA) transforms molecular level omics data
to the pathway level, enabling the discovery of patient-specific pathway signatures …