Drug addiction represents a dramatic dysregulation of motivational circuits that is caused by
a combination of exaggerated incentive salience and habit formation, reward deficits and …

Within the last two decades, many studies have addressed the clinical phenomenon of
Internet-use disorders, with a particular focus on Internet-gaming disorder. Based on …

Aberrant patterns of brain functional connectivity in the default mode network (DMN) have
been observed across different classes of substance use disorder (SUD) and are associated …

The loss of control over drug intake that occurs in addiction was initially believed to result
from disruption of subcortical reward circuits. However, imaging studies in addictive …

The amygdala integrates and processes incoming information pertinent to reward and to
emotions such as fear and anxiety that promote survival by warning of potential danger …

Human neuroimaging studies suggest that neural cue reactivity is strongly associated with
indices of drug use, including addiction severity and treatment success. However, little is …

Background Understanding the neural mechanisms of psychiatric disorders requires the use
of rodent models; however, frontal-striatal homologies between rodents and primates are …

Objective: The aim of this paper was to systematically review and meta-analyse the
prevalence of co-morbid psychiatric disorders (DSM-IV Axis I disorders) among treatment …

Scientific interest in “food addiction” is growing, but the topic remains controversial. One
critique of “food addiction” is its high degree of phenotypic overlap with binge eating …

Both drug addiction and obesity can be defined as disorders in which the saliency value of
one type of reward (drugs and food, respectively) becomes abnormally enhanced relative to …