Osteosarcoma is a primary bone tumor. Although it is a rare disease in general, it is the most
common primary bone tumor among children. Despite the significant advances made in the …

Tumors, a disease with a high mortality rate worldwide, have become a serious threat to
human health. Exonucleotide-5′-nucleotidase (CD73) is an emerging target for tumor …

Ferroptosis, which is characterized by the accumulation of intracellular iron and subsequent
lipid peroxidation, is a newly discovered form of regulated cell death and plays an important …

Lactate is abundant in cancer tissues due to active glycolysis (aka Warburg effect) and
mediates crosstalk between tumor cells and the immune microenvironment (TIME) to …

Targeted drug delivery is an advanced method that increases the concentration of drug in
the specific targeted area in the body. It improves efficacy of treatment and reduces the side …

In recent decades, various investigations have indicated that natural compounds have great
potential in the prevention and treatment of different chronic disorders including different …

Although new chemotherapy significantly increased the survival of breast cancer (BC)
patients, the use of these drugs is often associated with serious toxicity. The discovery of …

Despite major advances in the last 10 years, whether in terms of prevention or treatment, the
5 year survival rate remains relatively low for a large number of cancers. These therapeutic …

The neurodegeneration process begins in conjunction with the aging of the neurons. It
manifests in different parts of the brain as Aβ plaques, neurofibrillary tangles, Lewy bodies …

Background: Breast cancer is one of the most common malignancies affecting women
worldwide, emphasizing the need for effective therapeutic strategies. Phytochemicals …