Mitogen‐activated protein kinase (MAPK) signaling pathways organize a great constitution
network that regulates several physiological processes, like cell growth, differentiation, and …

Ionizing radiation, like a variety of other cellular stress factors, can activate or down-regulate
multiple signaling pathways, leading to either increased cell death or increased cell …

5-Lipoxygenase (ALOX5) is an iron-containing and nonheme dioxygenase that catalyzes
the peroxidation of polyunsaturated fatty acids such as arachidonic acid. ALOX5 is the rate …

Inflammation resolution counterbalances excessive inflammation and restores tissue
homeostasis after injury. Failure of resolution contributes to the pathology of numerous …

Endothelium homeostasis alterations govern the pathogenesis of cardiovascular diseases.
Several studies show that vitamins anti-oxidant proprieties rescue the endothelial functions …

Radiotherapy is one of the most common treatment modalities for controlling a wide range of
tumors. However, it has been shown that radiotherapy alone is unable to completely …

Wound healing is essential for skin repair after injury, and it consists of hemostasis,
inflammation, re-epithelialization, and remodeling phases. Successful re-epithelialization …

ERK1 and ERK2 (ERKs), two extracellular regulated kinases (ERK1/2), are evolutionary-
conserved and ubiquitous serine-threonine kinases involved in regulating cell signalling in …

Abstract Go-Ichi-Ni-San 2 (GINS2), as a newly discovered oncogene, is overexpressed in
several cancers. However, the specific role of GINS2 in the development of pancreatic …

Background The identification of signaling pathways that affect the cancer stem-like
phenotype may provide insights into therapeutic targets for combating embryonal …