Natural products in licorice for the therapy of liver diseases: Progress and future opportunities
X Li, R Sun, R Liu - Pharmacological Research, 2019 - Elsevier
Liver diseases related complications represent a significant source of morbidity and mortality
worldwide, creating a substantial economic burden. Oxidative stress, excessive …
worldwide, creating a substantial economic burden. Oxidative stress, excessive …
The pharmacological activities of licorice
R Yang, L Wang, B Yuan, Y Liu - Planta medica, 2015 - thieme-connect.com
Licorice is one of the oldest and most frequently used herbs in traditional Chinese medicine.
It contains more than 20 triterpenoids and 300 flavonoids. In recent years, a lot of studies …
It contains more than 20 triterpenoids and 300 flavonoids. In recent years, a lot of studies …
Molecular mechanisms underlying the anticancer activities of licorice flavonoids
Z Zhang, L Yang, J Hou, S Tian, Y Liu - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance Licorice has been commonly used in traditional Chinese
medicine for treatment of gastric, liver, and respiratory disease conditions for more than two …
medicine for treatment of gastric, liver, and respiratory disease conditions for more than two …
Role of licochalcone A in potential pharmacological therapy: a review
MT Li, L Xie, HM Jiang, Q Huang, RS Tong… - Frontiers in …, 2022 - frontiersin.org
Licochalcone A (LA), a useful and valuable flavonoid, is isolated from Glycyrrhiza uralensis
Fisch. ex DC. and widely used clinically in traditional Chinese medicine. We systematically …
Fisch. ex DC. and widely used clinically in traditional Chinese medicine. We systematically …
Role of plant-derived active constituents in cancer treatment and their mechanisms of action
Despite significant technological advancements in conventional therapies, cancer remains
one of the main causes of death worldwide. Although substantial progress has been made …
one of the main causes of death worldwide. Although substantial progress has been made …
Anticancer potential of natural chalcones: in vitro and in vivo evidence
R Michalkova, L Mirossay, M Kello… - International Journal of …, 2023 - mdpi.com
There is no doubt that significant progress has been made in tumor therapy in the past
decades. However, the discovery of new molecules with potential antitumor properties still …
decades. However, the discovery of new molecules with potential antitumor properties still …
[HTML][HTML] Licochalcone A induces autophagy through PI3K/Akt/mTOR inactivation and autophagy suppression enhances Licochalcone A-induced apoptosis of human …
JP Tsai, CH Lee, TH Ying, CL Lin, CL Lin, JT Hsueh… - Oncotarget, 2015 - ncbi.nlm.nih.gov
The use of dietary bioactive compounds in chemoprevention can potentially reverse,
suppress, or even prevent cancer progression. However, the effects of licochalcone A (LicA) …
suppress, or even prevent cancer progression. However, the effects of licochalcone A (LicA) …
Antitumor activity of dual blockade of PD-L1 and MEK in NSCLC patients derived three-dimensional spheroid cultures
CM Della Corte, G Barra, V Ciaramella… - Journal of Experimental …, 2019 - Springer
Abstract Background Anti-PD-1/PD-L1 drugs are effective as monotherapy in a proportion of
NSCLC patients and there is a strong rationale for combining them with targeted therapy …
NSCLC patients and there is a strong rationale for combining them with targeted therapy …
Cytotoxicity of trans-chalcone and licochalcone A against breast cancer cells is due to apoptosis induction and cell cycle arrest
LFB Bortolotto, FR Barbosa, G Silva… - Biomedicine & …, 2017 - Elsevier
Chalcones are precursors of flavonoids that exhibit structural heterogeneity and potential
antitumor activity. The objective of this study was to characterize the cytotoxicity of trans …
antitumor activity. The objective of this study was to characterize the cytotoxicity of trans …
Pharmacological effects and underlying mechanisms of licorice‐derived flavonoids
Y Wu, Z Wang, Q Du, Z Zhu, T Chen… - Evidence‐Based …, 2022 - Wiley Online Library
Glycyrrhizae Radix et Rhizoma is the most frequently prescribed natural medicine in China
and has been used for more than 2,000 years. The flavonoids of licorice have garnered …
and has been used for more than 2,000 years. The flavonoids of licorice have garnered …