Reinforcement learning detuned in addiction: integrative and translational approaches
Suboptimal decision-making strategies have been proposed to contribute to the
pathophysiology of addiction. Decision-making, however, arises from a collection of …
pathophysiology of addiction. Decision-making, however, arises from a collection of …
Biomarkers of relapse in cocaine use disorder: a narrative review
M Poireau, T Milpied, A Maillard, C Delmaire, E Volle… - Brain Sciences, 2022 - mdpi.com
Introduction: Cocaine use disorder is a chronic disease with severe consequences and a
high relapse rate. There is a critical need to explore the factors influencing relapse in order …
high relapse rate. There is a critical need to explore the factors influencing relapse in order …
Anatomical and functional connectivity of critical deep brain structures and their potential clinical application in brain stimulation
Subcortical structures, such as the hippocampus, amygdala, and nucleus accumbens
(NAcc), play crucial roles in human cognitive, memory, and emotional processing, chronic …
(NAcc), play crucial roles in human cognitive, memory, and emotional processing, chronic …
[HTML][HTML] Associations between anterior cingulate thickness, cingulum bundle microstructure, melancholia and depression severity in unipolar depression
N Mertse, N Denier, S Walther, S Breit… - Journal of affective …, 2022 - Elsevier
Background Structural and functional alterations of the anterior cingulate cortex (ACC) have
been related to emotional, cognitive and behavioral domains of major depressive disorder …
been related to emotional, cognitive and behavioral domains of major depressive disorder …
[HTML][HTML] Link between structural connectivity of the medial forebrain bundle, functional connectivity of the ventral tegmental area, and anhedonia in unipolar …
The ventral tegmental area (VTA), nucleus accumbens (NAcc), and prefrontal cortex (PFC)
are essential for experiencing pleasure and initiating motivated behaviour. The VTA, NAcc …
are essential for experiencing pleasure and initiating motivated behaviour. The VTA, NAcc …
Predictors of polysubstance use in patients with severe alcohol use disorder: the role of reward craving
M Di Nicola, M Pepe, S Montanari, L Bonomo… - Journal of Psychiatric …, 2023 - Elsevier
Background Different craving typologies (ie., reward, relief, obsessive) have been identified
in alcohol use disorder (AUD) but have been less investigated in specific populations like …
in alcohol use disorder (AUD) but have been less investigated in specific populations like …
Comparative basolateral amygdala connectomics reveals dissociable single-neuron projection patterns to frontal cortex in macaques and mice
Basolateral amygdala (BLA) is a key hub for affect in the brain, 1, 2, 3 and dysfunction within
this area contributes to a host of psychiatric disorders. 4, 5 BLA is extensively and …
this area contributes to a host of psychiatric disorders. 4, 5 BLA is extensively and …
Structure-function coupling within the reward network in preschool children predicts executive functioning in later childhood
SY Chan, ZY Ong, ZM Ngoh, YS Chong… - Developmental cognitive …, 2022 - Elsevier
Early differences in reward behavior have been linked to executive functioning
development. The nucleus accumbens (NAc) and orbitofrontal cortex (OFC) are activated by …
development. The nucleus accumbens (NAc) and orbitofrontal cortex (OFC) are activated by …
Diverging prefrontal cortex fiber connection routes to the subthalamic nucleus and the mesencephalic ventral tegmentum investigated with long range (normative) and …
VA Coenen, MD Döbrössy, SJ Teo… - Brain Structure and …, 2021 - Springer
Uncertainties concerning anatomy and function of cortico-subcortical projections have
arisen during the recent years. A clear distinction between cortico-subthalamic (hyperdirect) …
arisen during the recent years. A clear distinction between cortico-subthalamic (hyperdirect) …
Functional connectivity from dorsolateral prefrontal cortex mediates the impact of social jetlag on depressive tendency in young adults
Social jetlag (SJL), a form of circadian rhythm disturbance, is linked to depressive symptoms;
however, it is unclear what role the brain network, particularly the reward and cognitive …
however, it is unclear what role the brain network, particularly the reward and cognitive …