[HTML][HTML] Human papillomavirus-related oropharyngeal cancer

M Taberna, M Mena, MA Pavón, L Alemany… - Annals of …, 2017 - Elsevier
High-risk human papillomavirus (HPV) is now recognised as the principal cause of the
increasing incidence rates of oropharyngeal squamous cell carcinoma (OPSCC) in some …

Human papillomavirus in oropharyngeal cancer: The changing face of a disease

J Mallen-St Clair, M Alani, MB Wang… - Biochimica et Biophysica …, 2016 - Elsevier
The last decade has brought about an unexpected rise in oropharyngeal squamous cell
carcinoma (OPSCC) primarily in white males from the ages of 40–55 years, with limited …

CD4/CD8 ratio and cancer risk among adults with HIV

JL Castilho, A Bian, CA Jenkins… - JNCI: Journal of the …, 2022 - academic.oup.com
Background Independent of CD4 cell count, a low CD4/CD8 ratio in people with HIV (PWH)
is associated with deleterious immune senescence, activation, and inflammation, which may …

Prognostic Significance of the Microenvironment in Human Papillomavirus Oropharyngeal Carcinoma: A Systematic Review

R Baudouin, S Hans, Q Lisan, B Morin… - The …, 2024 - Wiley Online Library
Objective The immune microenvironment of HPV‐associated (HPV+) oropharyngeal
squamous cell carcinomas (OPSCCs)(HPV+ OPSCCs) differs from that of HPV‐independent …

The double-edged sword—How human papillomaviruses interact with immunity in head and neck cancer

H Wang, S Wang, YJ Tang, Y Chen, M Zheng… - Frontiers in …, 2019 - frontiersin.org
Patients with human papilloma virus (HPV)-associated head and neck squamous cell
carcinoma (HNSCC) have remarkably better prognosis, which differs from HPV-negative …

The tumor immune microenvironments of HPV+ and HPV head and neck cancers

SF Gameiro, AM Evans… - WIREs Mechanisms of …, 2022 - Wiley Online Library
Human papillomaviruses (HPVs) are the etiological agent of a significant, and increasing,
fraction of head and neck squamous cell carcinomas (HNSCC)—a heterogenous group of …

DNA damage baseline predicts resilience to space radiation and radiotherapy

E Pariset, A Bertucci, M Petay, S Malkani, AL Macha… - Cell reports, 2020 - cell.com
Deep space exploration will require real-time, minimally invasive monitoring of astronaut
health to mitigate the potential health impairments caused by space radiation and …

The role of the p16 and p53 tumor suppressor proteins and viral HPV16 E6 and E7 oncoproteins in the Assessment of Survival in patients with Head and Neck …

A Lifsics, M Cistjakovs, L Sokolovska, R Deksnis… - Cancers, 2023 - mdpi.com
Simple Summary The role of human papillomavirus (HPV) in the survival of patients with
head and neck squamous cell carcinoma (HNSCC) is an important topic. The recognition of …

Utility of CD8 score by automated quantitative image analysis in head and neck squamous cell carcinoma

DJ Hartman, F Ahmad, RL Ferris, DL Rimm… - Oral oncology, 2018 - Elsevier
Introduction In head and neck squamous cell carcinoma (HNSCC) high numbers of tumor
infiltrating CD8 T cells in the tumor microenvironment are associated with better outcome …

Tumor targeted genome editing mediated by a multi-functional gene vector for regulating cell behaviors

BY Liu, XY He, RX Zhuo, SX Cheng - Journal of controlled release, 2018 - Elsevier
For effective regulation of cell behaviors and prevention of tumor development by genome
editing, we constructed multi-functional self-assembled nanoparticles based on natural …