Tryptophan metabolism in the central nervous system: medical implications

JP Ruddick, AK Evans, DJ Nutt… - Expert reviews in …, 2006 - cambridge.org
The metabolism of the amino acid l-tryptophan is a highly regulated physiological process
leading to the generation of several neuroactive compounds within the central nervous …

Modeling the positive symptoms of schizophrenia in genetically modified mice: pharmacology and methodology aspects

M van den Buuse - Schizophrenia bulletin, 2010 - academic.oup.com
In recent years, there have been huge advances in the use of genetically modified mice to
study pathophysiological mechanisms involved in schizophrenia. This has allowed rapid …

Lactobacillus plantarum DR7 alleviates stress and anxiety in adults: a randomised, double-blind, placebo-controlled study

HX Chong, NAA Yusoff, YY Hor… - Beneficial …, 2019 - wageningenacademic.com
Probiotics have been reported to exert beneficial effects along the gut-brain axis. This
randomised, double-blind and placebo-controlled human study aimed to evaluate such …

The neurobiological basis of human aggression: a review on genetic and epigenetic mechanisms

R Waltes, AG Chiocchetti… - American Journal of …, 2016 - Wiley Online Library
Aggression is an evolutionary conserved behavior present in most species including
humans. Inadequate aggression can lead to longterm detrimental personal and societal …

Review and meta-analysis of antidepressant pharmacogenetic findings in major depressive disorder

M Kato, A Serretti - Molecular psychiatry, 2010 - nature.com
This systematic review summarizes pharmacogenetic studies on antidepressant response
and side effects. Out of the 17 genes we reviewed, 8 genes were entered into the meta …

Genetics of suicide

B Bondy, A Buettner, P Zill - Molecular psychiatry, 2006 - nature.com
The concept that genetic factors contribute to the complex trait of suicidal behaviour has
stimulated much work aimed at identifying susceptibility genes. So far molecular genetic …

Genetic determinants of aggression and impulsivity in humans

KA Pavlov, DA Chistiakov, VP Chekhonin - Journal of applied genetics, 2012 - Springer
Human aggression/impulsivity-related traits have a complex background that is greatly
influenced by genetic and non-genetic factors. The relationship between aggression and …

Genetics of human aggressive behaviour

IW Craig, KE Halton - Human genetics, 2009 - Springer
A consideration of the evolutionary, physiological and anthropological aspects of aggression
suggests that individual differences in such behaviour will have important genetic as well as …

The neurobiology of human aggressive behavior: neuroimaging, genetic, and neurochemical aspects

FA Cupaioli, FA Zucca, C Caporale, KP Lesch… - Progress in neuro …, 2021 - Elsevier
In modern societies, there is a strive to improve the quality of life related to risk of crimes
which inevitably requires a better understanding of brain determinants and mediators of …

Lactobacillus plantarum DR7 Modulated Bowel Movement and Gut Microbiota Associated with Dopamine and Serotonin Pathways in Stressed Adults

G Liu, HX Chong, FYL Chung, Y Li… - International journal of …, 2020 - mdpi.com
We have previously reported that the administration of Lactobacillus plantarum DR7 for 12
weeks reduced stress and anxiety in stressed adults as compared to the placebo group, in …