The packaging of genomic RNA in positive-sense single-stranded RNA viruses is a key part
of the viral infectious cycle, yet this step is not fully understood. Unlike double-stranded DNA …

3D structures of RNAs are the basis for understanding their biological functions. However,
experimentally solved RNA 3D structures are very limited in comparison with known RNA …

Virus capsids, the protective protein shells of viruses with typical dimensions in the
nanometer range, are a challenge to analyze. Analytical techniques need to characterize the …

The alphavirus capsid protein (Cp) selectively packages genomic RNA (gRNA) into the viral
nucleocapsid to produce infectious virus. Using photoactivatable ribonucleoside …

Capsid proteins often present a positively charged arginine-rich sequence at their terminal
regions, which has a fundamental role in genome packaging and particle stability for some …

Here we show the encapsulation of 35 nm diameter, nearly-spherical, DNA origami by self-
assembly of SV40-like (simian virus 40) particles. The self-assembly of this new type of …

Alphaviruses are enveloped positive-sense RNA viruses that can cause serious human
illnesses such as polyarthritis and encephalitis. Despite their widespread distribution and …

Viruses have been of interest to mankind since their discovery as small infectious agents in
the nineteenth century. Because many viruses cause diseases to humans and agriculture …

Alphaviruses are a serious threat to global health and can cause lethal encephalitic or
arthritogenic disease in humans and animals. As there are no licensed antivirals, it is critical …

Cryo-electron microscopy and tomography have allowed us to unveil the remarkable
structure of icosahedral viruses. However, in the past few years, the idea that these viruses …