Metal-free domino one-pot protocols for quinoline synthesis
Quinoline is one of the most widely investigated scaffolds by synthetic chemists because of
its medicinal importance. A wide range of metal-catalyzed, metal-free, multi-step or domino …
its medicinal importance. A wide range of metal-catalyzed, metal-free, multi-step or domino …
Advancements in the synthesis of fused tetracyclic quinoline derivatives
RA Mekheimer, MA Al-Sheikh, HY Medrasi… - RSC advances, 2020 - pubs.rsc.org
Fused tetracyclic systems containing a quinoline nucleus represent an important class of
heterocyclic bioactive natural products and pharmaceuticals because of their significant and …
heterocyclic bioactive natural products and pharmaceuticals because of their significant and …
Synthesis, structure–activity relationship of novel substituted 4H-chromen-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylates as potential anti-mycobacterial and anticancer …
Abstract Series of 4H-chromen-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylate derivatives 7a–
7zb, 8a–8d and 9a–9d were synthesized and screened for their in vitro anti-mycobacterial …
7zb, 8a–8d and 9a–9d were synthesized and screened for their in vitro anti-mycobacterial …
Recyclizations of 3-formylchromones with binucleophiles
AS Plaskon, OO Grygorenko, SV Ryabukhin - Tetrahedron, 2012 - Elsevier
Chromones are widely recognized as an important class of biologically active compounds of
both natural and synthetic origin. 1 e8 The less known but very useful application of the …
both natural and synthetic origin. 1 e8 The less known but very useful application of the …
3-Formylchromones as diverse building blocks in heterocycles synthesis
TES Ali, MA Ibrahim, NM El-Gohary… - European Journal of …, 2013 - eurjchem.com
This review covers the chemical reactivity of 3-formylchromones towards condensation
reactions with a variety of carbon and nitrogen nucleophiles. Some chromone derivatives …
reactions with a variety of carbon and nitrogen nucleophiles. Some chromone derivatives …
Trifluoromethyl vinamidinium salt as a promising precursor for fused β-trifluoromethyl pyridines
AP Mityuk, OM Kiriakov, VV Tiutiunnyk… - The Journal of …, 2023 - ACS Publications
An efficient chlorotrimethylsilane-promoted synthetic protocol for the preparation of
functionalized fused β-trifluoromethyl pyridines by cyclization of electron-rich …
functionalized fused β-trifluoromethyl pyridines by cyclization of electron-rich …
Synthesis, Molecular Docking, Molecular Dynamics Studies, and Biological Evaluation of 4H-Chromone-1,2,3,4-tetrahydropyrimidine-5-carboxylate Derivatives as …
Z Dolatkhah, S Javanshir, AS Sadr… - Journal of chemical …, 2017 - ACS Publications
A series of 4 H-chromone-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylates derivatives were
synthesized via a three component one-pot condensation of chromone-3-carbaldehyde …
synthesized via a three component one-pot condensation of chromone-3-carbaldehyde …
Solvent-free synthesis of functionalized pyridine derivatives using Wells-Dawson heteropolyacid as catalyst
Wells-Dawson heteropolyacids (H6P2W18O62· 24H2O) were used as catalysts in the
Hantzsch-like multicomponent condensation reaction with 3-formylchromones as aldehyde …
Hantzsch-like multicomponent condensation reaction with 3-formylchromones as aldehyde …
One-pot synthesis of highly functionalized bicyclic imidazopyridinium derivatives in ethanol
L Chen, R Huang, XX Du, SJ Yan… - … Sustainable Chemistry & …, 2017 - ACS Publications
A concise and eco-friendly route for the synthesis of highly functionalized bicyclic pyridinium
derivatives (3) via a one-pot reaction of chromone-3-carboxaldehydes (1) and N-benzyl nitro …
derivatives (3) via a one-pot reaction of chromone-3-carboxaldehydes (1) and N-benzyl nitro …
Synthesis of 4-quinolones, benzopyran derivatives and other fused systems based on the domino ANRORC reactions of (ortho-fluoro)-3-benzoylchromones
VO Iaroshenko, S Mkrtchyan, A Gevorgyan… - RSC Advances, 2015 - pubs.rsc.org
Herein we reported a transition metal free strategy for the synthesis of 4-quinolones,
benzopyran derivatives and other fused systems by the domino reaction of 3-benzoyl …
benzopyran derivatives and other fused systems by the domino reaction of 3-benzoyl …