Metal-free domino one-pot protocols for quinoline synthesis

JB Bharate, RA Vishwakarma, SB Bharate - RSC advances, 2015 - pubs.rsc.org
Quinoline is one of the most widely investigated scaffolds by synthetic chemists because of
its medicinal importance. A wide range of metal-catalyzed, metal-free, multi-step or domino …

Advancements in the synthesis of fused tetracyclic quinoline derivatives

RA Mekheimer, MA Al-Sheikh, HY Medrasi… - RSC advances, 2020 - pubs.rsc.org
Fused tetracyclic systems containing a quinoline nucleus represent an important class of
heterocyclic bioactive natural products and pharmaceuticals because of their significant and …

Synthesis, structure–activity relationship of novel substituted 4H-chromen-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylates as potential anti-mycobacterial and anticancer …

BC Raju, RN Rao, P Suman, P Yogeeswari… - Bioorganic & Medicinal …, 2011 - Elsevier
Abstract Series of 4H-chromen-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylate derivatives 7a–
7zb, 8a–8d and 9a–9d were synthesized and screened for their in vitro anti-mycobacterial …

Recyclizations of 3-formylchromones with binucleophiles

AS Plaskon, OO Grygorenko, SV Ryabukhin - Tetrahedron, 2012 - Elsevier
Chromones are widely recognized as an important class of biologically active compounds of
both natural and synthetic origin. 1 e8 The less known but very useful application of the …

3-Formylchromones as diverse building blocks in heterocycles synthesis

TES Ali, MA Ibrahim, NM El-Gohary… - European Journal of …, 2013 - eurjchem.com
This review covers the chemical reactivity of 3-formylchromones towards condensation
reactions with a variety of carbon and nitrogen nucleophiles. Some chromone derivatives …

Trifluoromethyl vinamidinium salt as a promising precursor for fused β-trifluoromethyl pyridines

AP Mityuk, OM Kiriakov, VV Tiutiunnyk… - The Journal of …, 2023 - ACS Publications
An efficient chlorotrimethylsilane-promoted synthetic protocol for the preparation of
functionalized fused β-trifluoromethyl pyridines by cyclization of electron-rich …

Synthesis, Molecular Docking, Molecular Dynamics Studies, and Biological Evaluation of 4H-Chromone-1,2,3,4-tetrahydropyrimidine-5-carboxylate Derivatives as …

Z Dolatkhah, S Javanshir, AS Sadr… - Journal of chemical …, 2017 - ACS Publications
A series of 4 H-chromone-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylates derivatives were
synthesized via a three component one-pot condensation of chromone-3-carbaldehyde …

Solvent-free synthesis of functionalized pyridine derivatives using Wells-Dawson heteropolyacid as catalyst

LM Sanchez, ÁG Sathicq, JL Jios, GT Baronetti… - Tetrahedron letters, 2011 - Elsevier
Wells-Dawson heteropolyacids (H6P2W18O62· 24H2O) were used as catalysts in the
Hantzsch-like multicomponent condensation reaction with 3-formylchromones as aldehyde …

One-pot synthesis of highly functionalized bicyclic imidazopyridinium derivatives in ethanol

L Chen, R Huang, XX Du, SJ Yan… - … Sustainable Chemistry & …, 2017 - ACS Publications
A concise and eco-friendly route for the synthesis of highly functionalized bicyclic pyridinium
derivatives (3) via a one-pot reaction of chromone-3-carboxaldehydes (1) and N-benzyl nitro …

Synthesis of 4-quinolones, benzopyran derivatives and other fused systems based on the domino ANRORC reactions of (ortho-fluoro)-3-benzoylchromones

VO Iaroshenko, S Mkrtchyan, A Gevorgyan… - RSC Advances, 2015 - pubs.rsc.org
Herein we reported a transition metal free strategy for the synthesis of 4-quinolones,
benzopyran derivatives and other fused systems by the domino reaction of 3-benzoyl …