Stress responses and related outcomes vary markedly across individuals. Elucidating the
molecular underpinnings of this variability is of great relevance for developing individualized …

Validated biological and psychological markers of acute stress in humans are an important
tool in translational research. The Trier Social Stress Test (TSST), involving public interview …

Aging and psychosocial stress are associated with increased inflammation and disease risk,
but the underlying molecular mechanisms are unclear. Because both aging and stress are …

Stressful experiences during early-life can modulate the genetic programming of specific
brain circuits underlying emotional and cognitive aspects of behavioral adaptation to …

A deeper understanding of the pathomechanisms leading to stress-related psychiatric
disorders is important for the development of more efficient preventive and therapeutic …

Childhood maltreatment is likely to influence fundamental biological processes and engrave
long-lasting epigenetic marks, leading to adverse health outcomes in adulthood. We aimed …

Following the discovery of glucocorticoid receptors in the hippocampus and other brain
regions, research has focused on understanding the effects of glucocorticoids in the brain …

Epigenetic alterations offer promise as diagnostic or prognostic markers, but it is not known
whether these measures associate with, or predict, clinical state. These questions were …

Epigenetic modifications in response to traumatic experience and stress are emerging as
important factors in the long-term biological trajectories leading to stress-related psychiatric …

Psychiatric phenotypes are multifactorial and polygenic, resulting from the complex interplay
of genes and environmental factors that act cumulatively throughout an organism's lifetime …