Cardiomyocyte maturation: advances in knowledge and implications for regenerative medicine
Our knowledge of pluripotent stem cell (PSC) biology has advanced to the point where we
now can generate most cells of the human body in the laboratory. PSC-derived …
now can generate most cells of the human body in the laboratory. PSC-derived …
3D printing of functional biomaterials for tissue engineering
Highlights•Comprehensive review of recent advances in 3D bioprinting techniques for tissue
engineering.•3D bioprinting provides complex 3D biomimetic architectures for 3D cell …
engineering.•3D bioprinting provides complex 3D biomimetic architectures for 3D cell …
Nanowired human cardiac organoid transplantation enables highly efficient and effective recovery of infarcted hearts
Human cardiac organoids hold remarkable potential for cardiovascular disease modeling
and human pluripotent stem cell–derived cardiomyocyte (hPSC-CM) transplantation. Here …
and human pluripotent stem cell–derived cardiomyocyte (hPSC-CM) transplantation. Here …
Mechanical communication in fibrosis progression
Mechanical hallmarks of fibrotic microenvironments are both outcomes and causes of
fibrosis progression. Understanding how cells sense and transmit mechanical cues in the …
fibrosis progression. Understanding how cells sense and transmit mechanical cues in the …
Interwoven aligned conductive nanofiber yarn/hydrogel composite scaffolds for engineered 3D cardiac anisotropy
Mimicking the anisotropic cardiac structure and guiding 3D cellular orientation play a critical
role in designing scaffolds for cardiac tissue regeneration. Significant advances have been …
role in designing scaffolds for cardiac tissue regeneration. Significant advances have been …
3D bioprinting of functional tissue models for personalized drug screening and in vitro disease modeling
Abstract 3D bioprinting is emerging as a promising technology for fabricating complex tissue
constructs with tailored biological components and mechanical properties. Recent advances …
constructs with tailored biological components and mechanical properties. Recent advances …
Stem cell therapy in heart diseases–cell types, mechanisms and improvement strategies
P Müller, H Lemcke, R David - Cellular Physiology and Biochemistry, 2018 - karger.com
A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …
approach for the treatment of cardiovascular diseases. Since the first transplantation into …
Electrospun conductive nanofibrous scaffolds for engineering cardiac tissue and 3D bioactuators
Mimicking the nanofibrous structure similar to extracellular matrix and conductivity for
electrical propagation of native myocardium would be highly beneficial for cardiac tissue …
electrical propagation of native myocardium would be highly beneficial for cardiac tissue …
Preclinical and clinical development of noncoding RNA therapeutics for cardiovascular disease
RNA modulation has become a promising therapeutic approach for the treatment of several
types of disease. The emerging field of noncoding RNA-based therapies has now come to …
types of disease. The emerging field of noncoding RNA-based therapies has now come to …
Injectable fullerenol/alginate hydrogel for suppression of oxidative stress damage in brown adipose-derived stem cells and cardiac repair
Stem cell implantation strategy has exhibited potential to treat the myocardial infarction (MI),
however, the low retention and survival limit their applications due to the reactive oxygen …
however, the low retention and survival limit their applications due to the reactive oxygen …