B-cell lymphomas are a group of heterogeneous neoplasms resulting from the clonal
expansion of mature B cells arrested at various stages of differentiation. Specifically, two …

Abstract Purpose Three dimensional (3D)“in vitro” models are progressively being applied to
investigate tumor cell biology and the interaction of cancer cells with tumor …

Non-Hodgkin B-cell lymphomas (B-NHL) mainly develop within lymph nodes as aggregates
of tumor cells densely packed with their surrounding microenvironment, creating a tumor …

Background Follicular lymphoma (FL), the most common indolent non-Hodgkin's
Lymphoma, is a heterogeneous disease and a paradigm of the contribution of immune …

In vitro cell cultures are fundamental and necessary tools in cancer research and
personalized drug discovery. Currently, most cells are cultured using two-dimensional (2D) …

Follicular lymphoma (FL), the most common indolent non-Hodgkin lymphoma, constitutes a
paradigm of immune tumor microenvironment (TME) contribution to disease onset …

Purpose B-cell non-Hodgkin lymphomas (B-NHLs) are the most common
lymphoproliferative malignancy. Despite targeted therapies, the bone marrow involvement …

Large-scale compound screens are a powerful model system for understanding variability of
treatment response and discovering druggable tumor vulnerabilities of hematological …

Cell culture is an important life science technology. Compared with the traditional two-
dimensional cell culture, three-dimensional cell culture can simulate the natural environment …

Abstract Background & Aims Although specialized and dedicated to the production of
digestive enzymes, pancreatic acinar cells harbor a high plasticity and are able to modify …