Non-alcoholic fatty liver disease (NAFLD), type 2 diabetes, and non-viral hepatocarcinoma: Pathophysiological mechanisms and new therapeutic strategies

E Vetrano, L Rinaldi, A Mormone, C Giorgione… - Biomedicines, 2023 - mdpi.com
In recent years, the incidence of non-viral hepatocellular carcinoma (HCC) has increased
dramatically, which is probably related to the increased prevalence of metabolic syndrome …

Liver fibrosis and MAFLD: the exploration of multi-drug combination therapy strategies

Q Dong, H Bao, J Wang, W Shi, X Zou, J Sheng… - Frontiers in …, 2023 - frontiersin.org
In recent years, the prevalence of metabolic-associated fatty liver disease (MAFLD) has
reached pandemic proportions as a leading cause of liver fibrosis worldwide. However, the …

New roles of N6-methyladenosine methylation system regulating the occurrence of non-alcoholic fatty liver disease with N6-methyladenosine-modified MYC

W Cheng, M Li, L Zhang, C Zhou, S Yu… - Frontiers in …, 2022 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) has become a major chronic disease in
contemporary society, affected by N6-methyladenosine (m6A) RNA methylation, one of the …

Low-carbohydrate and low-fat diet with metabolic-dysfunction-associated fatty liver disease

C Hu, R Huang, R Li, N Ning, Y He, J Zhang, Y Wang… - Nutrients, 2023 - mdpi.com
Background: This observational cross-sectional study was designed to explore the effects of
a low-carbohydrate diet (LCD) and a low-fat diet (LFD) on metabolic-dysfunction-associated …

Obesity under the moonlight of c-MYC

YA Nevzorova, FJ Cubero - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
The moonlighting protein c-Myc is a master regulator of multiple biological processes
including cell proliferation, differentiation, angiogenesis, apoptosis and metabolism. It is …

Traditional Chinese medicines and natural products targeting immune cells in the treatment of metabolic-related fatty liver disease

Z Li, H Ouyang, J Zhu - Frontiers in Pharmacology, 2023 - frontiersin.org
MAFLD stands for metabolic-related fatty liver disease, which is a prevalent liver disease
affecting one-third of adults worldwide, and is strongly associated with obesity …

Abnormal metabolism in hepatic stellate cells: Pandora's box of MAFLD related hepatocellular carcinoma

Y Sun, H Zhang, Y Li, J Han - Biochimica et Biophysica Acta (BBA)-Reviews …, 2024 - Elsevier
Metabolic associated fatty liver disease (MAFLD) is a significant risk factor for the
development of hepatocellular carcinoma (HCC). Hepatic stellate cells (HSCs), as key …

Bioinspired Photonic Microchip with Molecularly Imprinted Polymer for Single Recognition of c‐Myc Protein in Predictive Medical Diagnostics

J Xu, X Liu, Y Sun, D Zhang, H Zhou… - Advanced Healthcare …, 2023 - Wiley Online Library
Monitoring of trace c‐Myc protein as the biomarker of ubiquitous cancers is critical in
achieving predictive medical diagnostics. However, qualitative and quantitative detection of …

[HTML][HTML] Insight into the regulatory mechanism of m6A modification: From MAFLD to hepatocellular carcinoma

X Zha, Z Gao, M Li, X Xia, Z Mao, S Wang - Biomedicine & …, 2024 - Elsevier
In recent years, there has been a significant increase in the incidence of metabolic-
associated fatty liver disease (MAFLD), which has been attributed to the increasing …

[HTML][HTML] Rifaximin on epigenetics and autophagy in animal model of hepatocellular carcinoma secondary to metabolic-dysfunction associated steatotic liver disease

MT Michalczuk, L Longo, MB Keingeski… - World Journal of …, 2024 - ncbi.nlm.nih.gov
Rifaximin on epigenetics and autophagy in animal model of hepatocellular carcinoma
secondary to metabolic-dysfunction associated steatotic liver disease - PMC Back to Top Skip …