Radical thiol-ene chemistry has been demonstrated for a range of applications in peptide
science, including macrocyclization, glycosylation and lipidation amongst a myriad of others …

Click chemistry was extensively used to decorate synthetic multivalent scaffolds with glycans
to mimic the cell surface glycocalyx and to develop applications in glycosciences …

The last decade has witnessed a series of discoveries that question the traditional paradigm
of multivalency as a “safe” strategy to enhance the binding affinity of a lectin receptor to its …

The vision of multivalency as a strategy limited to achieve affinity enhancements between a
protein receptor and its putative sugar ligand (glycotope) has proven too simplistic. On the …

Well-defined heterofunctionalized glycosylated scaffolds with unprecedented molecular
combinations have been prepared using up to five different bioorthogonal ligations. This …

Carbohydrate–protein interactions (CPIs) are involved in a wide range of biological
phenomena. Hence, the characterization and presentation of carbohydrate epitopes that …

The design and synthesis of multivalent ligands displaying complex oligosaccharides is
necessary for the development of therapeutics, diagnostics, and research tools. Here, we …

Cyclopeptides have recently emerged as attractive molecular scaffolds for the multivalent
presentation of carbohydrates in a well-defined constrained spatial orientation. This mini …

The synthesis of heteroglycoclusters (hGCs) is being subjected to rising interest, owing to
their potential applications in glycobiology. In this paper, we report an efficient and …

N‐Alkyl‐thio glycolipids (TGL) are proposed as fundamental components in the production
of synthetic outer membrane vesicles (S‐OMVs). A small but representative library of …