The blood-testis barrier and its implications for male contraception
CY Cheng, DD Mruk - Pharmacological reviews, 2012 - ASPET
The blood-testis barrier (BTB) is one of the tightest blood-tissue barriers in the mammalian
body. It divides the seminiferous epithelium into the basal and the apical (adluminal) …
body. It divides the seminiferous epithelium into the basal and the apical (adluminal) …
Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis
DD Mruk, CY Cheng - Endocrine reviews, 2004 - academic.oup.com
Spermatogenesis is the process by which a single spermatogonium develops into 256
spermatozoa, one of which will fertilize the ovum. Since the 1950s when the stages of the …
spermatozoa, one of which will fertilize the ovum. Since the 1950s when the stages of the …
Spermiation: the process of sperm release
Spermiation is the process by which mature spermatids are released from Sertoli cells into
the seminiferous tubule lumen prior to their passage to the epididymis. It takes place over …
the seminiferous tubule lumen prior to their passage to the epididymis. It takes place over …
Crosstalk between Sertoli and germ cells in male fertility
S Wu, M Yan, R Ge, CY Cheng - Trends in molecular medicine, 2020 - cell.com
Spermatogenesis is supported by intricate crosstalk between Sertoli cells and germ cells
including spermatogonia, spermatocytes, haploid spermatids, and spermatozoa, which …
including spermatogonia, spermatocytes, haploid spermatids, and spermatozoa, which …
Cell junction dynamics in the testis: Sertoli-germ cell interactions and male contraceptive development
CY Cheng, DD Mruk - Physiological reviews, 2002 - journals.physiology.org
Spermatogenesis is an intriguing but complicated biological process. However, many
studies since the 1960s have focused either on the hormonal events of the hypothalamus …
studies since the 1960s have focused either on the hormonal events of the hypothalamus …
[PDF][PDF] Proliferation and differentiation of spermatogonial stem cells
DG de Rooij - Reproduction-Cambridge-, 2001 - scholar.archive.org
Spermatogonial stem cells (As spermatogonia) are single cells that either renew themselves
or produce Apr (paired) spermatogonia predestined to differentiate. In turn, the Apr divide …
or produce Apr (paired) spermatogonia predestined to differentiate. In turn, the Apr divide …
β1- and α6-integrin are surface markers on mouse spermatogonial stem cells
T Shinohara, MR Avarbock… - Proceedings of the …, 1999 - National Acad Sciences
Although spermatogenesis is essential for reproduction, little is known about spermatogonial
stem cells. These cells provide the basis for spermatogenesis throughout adult life by …
stem cells. These cells provide the basis for spermatogenesis throughout adult life by …
[PDF][PDF] Identification of specific sites of hormonal regulation in spermatogenesis in rats, monkeys, and man
RI McLachlan, L O'Donnell, SJ Meachem… - Recent progress in …, 2002 - researchgate.net
ABSTRACT A detailed understanding of the hormonal regulation of spermatogenesis is
required for the informed assessment and management of male fertility and, conversely, for …
required for the informed assessment and management of male fertility and, conversely, for …
The acrosome-acroplaxome-manchette complex and the shaping of the spermatid head
AL Kierszenbaum, LL Tres - Archives of histology and cytology, 2004 - jstage.jst.go.jp
A combination of exogenous contractile forces generated by a stack of F-actin-containing
hoops embracing the apical region of the elongating spermatid nucleus and an endogenous …
hoops embracing the apical region of the elongating spermatid nucleus and an endogenous …
The Sertoli cell cytoskeleton
AW Vogl, KS Vaid, JA Guttman - Molecular mechanisms in …, 2008 - Springer
The cytoskeleton of terminally differentiated mammalian Sertoli cells is one of the most
elaborate of those that have been described for cells in tissues. Actin filaments, intermediate …
elaborate of those that have been described for cells in tissues. Actin filaments, intermediate …