Facial nerve repair: bioengineering approaches in preclinical models

FB Bengur, C Stoy, MA Binko, WV Nerone… - … Engineering Part B …, 2022 - liebertpub.com
Injury to the facial nerve can occur after different etiologies and range from simple
transection of the branches to varying degrees of segmental loss. Management depends on …

Interchangeable role of motor cortex and reafference for the stable execution of an orofacial action

MA Elbaz, M Demers, D Kleinfeld, C Ethier… - Journal of …, 2023 - Soc Neuroscience
Animals interact with their environment through mechanically active, mobile sensors. The
efficient use of these sensory organs implies the ability to track their position; otherwise …

Toward the bionic face: a novel neuroprosthetic device paradigm for facial reanimation consisting of neural blockade and functional electrical stimulation

N Jowett, RE Kearney, CJ Knox… - Plastic and …, 2019 - journals.lww.com
Background: Facial palsy is a devastating condition potentially amenable to rehabilitation by
functional electrical stimulation. Herein, a novel paradigm for unilateral facial reanimation …

Autonomic nerve fibers aberrantly reinnervate denervated facial muscles and alter muscle fiber population

V Tereshenko, DC Dotzauer, M Luft… - Journal of …, 2022 - Soc Neuroscience
The surgical redirection of efferent neural input to a denervated muscle via a nerve transfer
can reestablish neuromuscular control after nerve injuries. The role of autonomic nerve …

Rat whisker movement after facial nerve lesion: evidence for autonomic contraction of skeletal muscle

JT Heaton, SH Sheu, MH Hohman, CJ Knox… - Neuroscience, 2014 - Elsevier
Vibrissal whisking is often employed to track facial nerve regeneration in rats; however, we
have observed similar degrees of whisking recovery after facial nerve transection with or …

Outcome measures of facial nerve regeneration: a review of murine model systems

MA Chacon, SR Echternacht, JI Leckenby - Annals of Anatomy …, 2020 - Elsevier
Animal models of nerve function have been subject to extensive study in order to understand
and investigate methods which may improve axon regeneration and promote functional …

Efficacy of LED photobiomodulation for functional and axonal regeneration after facial nerve section-suture

H Er-Rouassi, L Benichou, B Lyoussi, C Vidal - Frontiers in Neurology, 2022 - frontiersin.org
Facial nerve damage can lead to partial or total facial nerve palsy. Photobiomodulation has
been reported to improve and accelerate functional recovery following peripheral nerve …

Electrophysiological assessment of a peptide amphiphile nanofiber nerve graft for facial nerve repair

JJ Greene, MT McClendon… - Journal of tissue …, 2018 - Wiley Online Library
Facial nerve injury can cause severe long‐term physical and psychological morbidity. There
are limited repair options for an acutely transected facial nerve not amenable to primary …

Facial nerve repair: fibrin adhesive coaptation versus epineurial suture repair in a rodent model

CJ Knox, MH Hohman, IJ Kleiss… - The …, 2013 - Wiley Online Library
Objectives/Hypothesis Repair of the transected facial nerve has traditionally been
accomplished with microsurgical neurorrhaphy; however, fibrin adhesive coaptation (FAC) …

Facial nerve regeneration using silicone conduits filled with ammonia-functionalized graphene oxide and frankincense-embedded hydrogel

S Aghajanian, A Taghi Doulabi, M Akhbari… - Inflammation and …, 2021 - Springer
Background Silicone tube (ST) conduits have been accepted as a therapeutic alternative to
direct nerve suturing in the treatment of nerve injuries; however, the search for optimal …