[HTML][HTML] Peptide therapeutics from venom: Current status and potential

MW Pennington, A Czerwinski, RS Norton - Bioorganic & medicinal …, 2018 - Elsevier
Peptides are recognized as being highly selective, potent and relatively safe as potential
therapeutics. Peptides isolated from the venom of different animals satisfy most of these …

The toxicogenomic multiverse: convergent recruitment of proteins into animal venoms

BG Fry, K Roelants, DE Champagne… - Annual review of …, 2009 - annualreviews.org
Throughout evolution, numerous proteins have been convergently recruited into the venoms
of various animals, including centipedes, cephalopods, cone snails, fish, insects (several …

[HTML][HTML] Why do we study animal toxins?

Y Zhang - Zoological research, 2015 - ncbi.nlm.nih.gov
Venom (toxins) is an important trait evolved along the evolutionary tree of animals. Our
knowledges on venoms, such as their origins and loss, the biological relevance and the …

Kallikreins on steroids: structure, function, and hormonal regulation of prostate-specific antigen and the extended kallikrein locus

MG Lawrence, J Lai, JA Clements - Endocrine reviews, 2010 - academic.oup.com
The 15 members of the kallikrein-related serine peptidase (KLK) family have diverse tissue-
specific expression profiles and putative proteolytic functions. The kallikrein family is also …

Venom evolution through gene duplications

ESW Wong, K Belov - Gene, 2012 - Elsevier
Venoms contain highly complex mixtures that typically include hundreds of different
components and have evolved independently in a diverse range of animals including …

An ancient, conserved gene regulatory network led to the rise of oral venom systems

A Barua, AS Mikheyev - Proceedings of the National …, 2021 - National Acad Sciences
Oral venom systems evolved multiple times in numerous vertebrates, enabling the
exploitation of unique predatory niches. Yet how and when they evolved remains poorly …

[图书][B] The biology of small mammals

JF Merritt - 2010 - books.google.com
2010 Outstanding Academic Title, Choice Magazine The Biology of Small Mammals is the
first exploration of the lives of small mammals undertaken in decades. Mammalogist Joseph …

Surface loops of trypsin-like serine proteases as determinants of function

P Goettig, H Brandstetter, V Magdolen - Biochimie, 2019 - Elsevier
Trypsin and chymotrypsin-like serine proteases from family S1 (clan PA) constitute the
largest protease group in humans and more generally in vertebrates. The prototypes …

[HTML][HTML] Mad, bad and dangerous to know: the biochemistry, ecology and evolution of slow loris venom

K Nekaris, RS Moore, EJ Rode, BG Fry - Journal of Venomous …, 2013 - SciELO Brasil
Only seven types of mammals are known to be venomous, including slow lorises
(Nycticebus spp.). Despite the evolutionary significance of this unique adaptation amongst …

Never, Ever make an enemy… out of an anemone: Transcriptomic comparison of clownfish hosting sea anemone venoms

A Delgado, C Benedict, J Macrander, M Daly - Marine Drugs, 2022 - mdpi.com
Sea anemones are predatory marine invertebrates and have diverse venom arsenals.
Venom is integral to their biology, and is used in competition, defense, and feeding. Three …