Multifunctional polymeric micelle-based nucleic acid delivery: Current advances and future perspectives

I Jarak, M Pereira-Silva, AC Santos, F Veiga… - Applied Materials …, 2021 - Elsevier
Nucleic acid (NA) therapeutics are a rapidly growing class of biomedicines with the ability to
manipulate gene expression in potent and specific manner, and with the enormous potential …

Fluorescent assemblies: Synergistic of amphiphilic molecules and fluorescent elements

J Yuan, S Dong, J Hao - Current Opinion in Colloid & Interface Science, 2023 - Elsevier
In recent years, fluorescent assemblies based amphiphilic molecules have gained attention
as unique and powerful materials for multiple applications that cover sensors …

Orthogonal light-activated DNA for patterned biocomputing within synthetic cells

D Hartmann, R Chowdhry, JM Smith… - Journal of the American …, 2023 - ACS Publications
Cell-free gene expression is a vital research tool to study biological systems in defined
minimal environments and has promising applications in biotechnology. Developing …

Nucleic acids based polyelectrolyte complexes: Their complexation mechanism, morphology, and stability

YH Kim, K Lee, S Li - Chemistry of Materials, 2021 - ACS Publications
Nucleic acids are a special class of negatively charged polymers, and they can complex with
cationic small molecules and polymers to form polyelectrolyte complexes of rich …

Endogenous tumor microenvironment-responsive multifunctional nanoplatforms for precision cancer theranostics

C Wang, S Ding, S Wang, Z Shi, NK Pandey… - Coordination Chemistry …, 2021 - Elsevier
Multifunctional nanoplatforms (MFNPs) have attracted increasing attention because of their
ability to integrate diverse functional diagnostic and therapeutic agents in one system …

A review of stimuli-responsive polymeric micelles for tumor-targeted delivery of curcumin

N Qiu, X Du, J Ji, G Zhai - Drug Development and Industrial …, 2021 - Taylor & Francis
Despite a potential drug with multiple pharmacological activities, curcumin has
disadvantages of the poor water solubility, rapid metabolism, low bioavailability, which …

Recent advances in biomedical applications of cholic acid-based macromolecules

S Sahoo, P Ghosh, S Banerjee… - ACS Applied Polymer …, 2021 - ACS Publications
In recent decades, polymeric materials have been extensively investigated for their
widespread therapeutic applications in various biomedical fields. In particular, biomolecule …

Polymeric-Micelle-Based delivery systems for nucleic acids

G Sinani, ME Durgun, E Cevher, Y Özsoy - Pharmaceutics, 2023 - mdpi.com
Nucleic acids can modulate gene expression specifically. They are increasingly being
utilized and show huge potential for the prevention or treatment of various diseases …

Micelleplex-based nucleic acid therapeutics: From targeted stimuli-responsiveness to nanotoxicity and regulation

M Pereira-Silva, I Jarak, AC Santos, F Veiga… - European Journal of …, 2020 - Elsevier
Cell-targeted nucleic acid (NA) therapeutics, either DNA-or RNA-based, have experienced
considerable attention regarding their potential applications in gene expression modulation …

Smart polymeric nanostructures for targeted delivery of therapeutics

M Dhara - Journal of Macromolecular Science, Part A, 2020 - Taylor & Francis
In recent times, research at the interface of polymer chemistry and biology has been going
through a tremendous progress. A lot of interesting works have focused toward synthesis of …