Synapses are intercellular junctions specialized for fast, point-to-point information transfer
from a presynaptic neuron to a postsynaptic cell. At a synapse, a presynaptic terminal …

Synapse organizing proteins are multifaceted molecules that coordinate the complex
processes of brain development and plasticity at the level of individual synapses. Their …

Proteins critical for synaptic transmission are non-uniformly distributed and assembled into
regions of high density called subsynaptic densities (SSDs) that transsynaptically align in …

Recent evidence suggests that nano-organization of proteins within synapses may control
the strength of communication between neurons in the brain. The unique subsynaptic …

The spatiotemporal organization of neurotransmitter receptors in the postsynaptic
membrane is a fundamental determinant of synaptic transmission and thus of information …

To correctly transfer information, neuronal networks need to continuously adjust their
synaptic strength to extrinsic stimuli. This ability, termed synaptic plasticity, is at the heart of …

Long-term potentiation (LTP) of excitatory synaptic strength, which has long been
considered a synaptic correlate for learning and memory, requires a fast recruitment of …

The synaptic cleft has been vastly investigated in the last decades, leading to a novel and
fascinating model of the functional and structural modifications linked to synaptic …

Long-term potentiation (LTP) has long been considered as an important cellular mechanism
for learning and memory. LTP expression involves NMDA receptor-dependent synaptic …

Synapses are organized into nanocolumns that control synaptic transmission efficacy
through precise alignment of postsynaptic neurotransmitter receptors and presynaptic …