Epidemiology of obesity and diabetes and their cardiovascular complications

SN Bhupathiraju, FB Hu - Circulation research, 2016 - Am Heart Assoc
Obesity and diabetes mellitus have reached epidemic proportions in the past few years.
During 2011 to 2012, more than one-third of the US population was obese. Although recent …

Metabolically healthy obesity: definitions, determinants and clinical implications

CM Phillips - Reviews in Endocrine and Metabolic Disorders, 2013 - Springer
Obesity is associated with increased risk of developing metabolic syndrome (MetS), type 2
diabetes mellitus (T2DM) and cardiovascular disease (CVD) leading to higher all-cause …

Metabolically healthy obesity across the life course: epidemiology, determinants, and implications

CM Phillips - Annals of the New York Academy of Sciences, 2017 - Wiley Online Library
In recent years, different subphenotypes of obesity have been described, including
metabolically healthy obesity (MHO), in which a proportion of obese individuals, despite …

Risk of developing diabetes and cardiovascular disease in metabolically unhealthy normal-weight and metabolically healthy obese individuals

KK Aung, C Lorenzo, MA Hinojosa… - The Journal of Clinical …, 2014 - academic.oup.com
Context: The risk of cardiovascular disease (CVD) and type 2 diabetes mellitus (DM)
associated with obesity appears to be influenced by the coexistence of other metabolic …

Prevalence of metabolically healthy obese and metabolically obese but normal weight in adults worldwide: a meta-analysis

B Wang, R Zhuang, X Luo, L Yin… - Hormone and …, 2015 - thieme-connect.com
The objective of the present study was to summarize the prevalence and influencing factors
of metabolically healthy obese (MHO) and metabolically obese but normal weight (MONW) …

Molecular insights into the role of white adipose tissue in metabolically unhealthy normal weight and metabolically healthy obese individuals

F Badoud, M Perreault, MA Zulyniak… - The FASEB …, 2015 - Wiley Online Library
Obesity is a risk factor for the development of type 2 diabetes and cardiovascular disease.
However, it is now recognized that a subset of individuals have reduced cardiometabolic risk …

Metabolic health and weight: Understanding metabolically unhealthy normal weight or metabolically healthy obese patients

H Mathew, OM Farr… - Metabolism-Clinical and …, 2016 - metabolismjournal.com
Obesity is most commonly defined as a BMI of over 30 kg/m2. Typical classification is into
categories of Class I (BMI> 30 kg/m2), Class II (BMI equal to or over 35 kg/m2) and Class III …

Adiponectin levels differentiate metabolically healthy vs unhealthy among obese and nonobese white individuals

S Ahl, M Guenther, S Zhao, R James… - The Journal of …, 2015 - academic.oup.com
Context: Adiponectin levels (ADPN) are lower in individuals with central obesity and
cardiometabolic diseases. Conversely, studies have shown paradoxical …

Phenotyping obesity: a focus on metabolically healthy obesity and metabolically unhealthy normal weight

R Agius, NP Pace, S Fava - Diabetes/Metabolism Research and …, 2024 - Wiley Online Library
Over the past 4 decades, research has shown that having a normal body weight does not
automatically imply preserved metabolic health and a considerable number of lean …

[HTML][HTML] Metabolic health, obesity, and the risk of developing open-angle glaucoma: metabolically healthy obese patients versus metabolically unhealthy but normal …

Y Jung, K Han, HYL Park, SH Lee… - … & metabolism journal, 2020 - synapse.koreamed.org
Background This study sought to investigate the associations between metabolic health
status, obesity, and incidence of primary open-angle glaucoma (POAG). Methods In this …