Trends in life expectancy of HIV-positive adults on antiretr... : Current Opinion in HIV and
AIDS Trends in life expectancy of HIV-positive adults on antiretroviral therapy across the …

The unprecedented medical achievements of the last century have dramatically improved
our quality of life. Today, the high cost of many healthcare approaches challenges their long …

Importance Antiretroviral therapy (ART) has improved life expectancy for individuals with HIV
infection, but recent data comparing life span and comorbidity-free years by HIV status are …

Objectives Life expectancy is an important indicator informing decision making in policies
relating to HIV‐infected people. Studies estimating life expectancy after starting combination …

Age-associated comorbidities (cardiovascular and renal disease) were more prevalent
among HIV-positive compared with HIV-uninfected patients. Comorbidity was associated …

Background Combination antiretroviral therapy (ART) has significantly increased survival
among HIV-positive adults in the United States (US) and Canada, but gains in life …

Background: It is unknown if a survival gap remains between HIV-infected and HIV-
uninfected individuals with access to care. Methods: We conducted a cohort study within …

Macrophages promote an early host response to infection by releasing pro-inflammatory
cytokines such as interleukin-1β (IL-1β), TNF, and IL-6. The bioactivity of IL-1β is classically …

Highlights•With no available cure, treatment of HIV infection requires life-long therapy.•A
combination of three drugs is the current standard for chronic HIV therapy.•Multiple single …

Combination antiretroviral therapy (cART) reduces HIV-associated morbidities and
mortalities but cannot cure the infection. Given the difficulty of eradicating HIV-1, a functional …