Abstract The Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism is
associated with various diseases (vascular, cancers, neurology, diabetes, psoriasis, etc) …

Background: Genetic and environmental factors play important roles in pathogenesis of
digestive tract cancers like those in the esophagus, stomach and colorectum. Folate …

Background: The MTHFR C677T polymorphism is a genetic alteration affecting an enzyme
involved in folate metabolism, but its relationship to host susceptibility to prostate cancer …

We assess the contributions of genetic variants for the enzymes involved in capecitabine
metabolism to colorectal cancer (CRC) development risk. In this case-control study, DNA …

The association between methylenetetrahydrofolate reductase (MTHFR) C677T
polymorphism and colorectal cancer (CRC) susceptibility has been researched in numerous …

Background: Breast cancer is a major cause of morbidity and mortality in Jordan and
worldwide. Abnormality of DNA methylation is a possible mechanism for the development of …

In recent years, increasing evidence has implicated the importance of mutations in the
MTHFR gene in the risk of gastric cancer risk. A single nucleotide polymorphism (SNP) in …

Association analysis of C677T and A1298C polymorphisms in MTHFR gene in patients with
colorectal cancer susceptibility Page 1 74 Central Asian Journal of Medical and Pharmaceutical …

Background Methylenetetrahydrofolate reductase (MTHFR), a critical enzyme in folate
metabolism is involved in DNA synthesis, DNA repair and DNA methylation. The functional …

Objectives: The aim of the study was to evaluate the frequency of the 677C> T and 1298A>
C polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) gene, as well as the …