Flavonoids and their anti-diabetic effects: Cellular mechanisms and effects to improve blood sugar levels

RK Al-Ishaq, M Abotaleb, P Kubatka, K Kajo… - Biomolecules, 2019 - mdpi.com
Diabetes mellitus (DM) is a prevailing global health metabolic disorder, with an alarming
incidence rate and a huge burden on health care providers. DM is characterized by the …

Neurobiology of food intake in health and disease

GJ Morton, TH Meek, MW Schwartz - Nature Reviews Neuroscience, 2014 - nature.com
Under normal conditions, food intake and energy expenditure are balanced by a
homeostatic system that maintains stability of body fat content over time. However, this …

Diabetes and cognitive dysfunction

RJ McCrimmon, CM Ryan, BM Frier - The Lancet, 2012 - thelancet.com
Cognitive dysfunction in type 1 and type 2 diabetes share many similarities, but important
differences do exist. A primary distinguishing feature of type 2 diabetes is that people with …

Efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes: the DEPICT-1 52-week study

P Dandona, C Mathieu, M Phillip, L Hansen… - Diabetes …, 2018 - Am Diabetes Assoc
OBJECTIVE This study evaluated the long-term safety and efficacy of dapagliflozin as an
adjunct to adjustable insulin in patients with type 1 diabetes and inadequate glycemic …

Energy metabolism of the brain, including the cooperation between astrocytes and neurons, especially in the context of glycogen metabolism

A Falkowska, I Gutowska, M Goschorska… - International journal of …, 2015 - mdpi.com
Glycogen metabolism has important implications for the functioning of the brain, especially
the cooperation between astrocytes and neurons. According to various research data, in a …

Hydrogels in emerging technologies for type 1 diabetes

S Fuchs, AU Ernst, LH Wang, K Shariati… - Chemical …, 2020 - ACS Publications
Type 1 diabetes therapies that afford tighter glycemic control in a more manageable and
painless manner for patients has remained a central focus of next-generation diabetes …

Obesity in type 1 diabetes: pathophysiology, clinical impact, and mechanisms

KD Corbin, KA Driscoll, RE Pratley, SR Smith… - Endocrine …, 2018 - academic.oup.com
There has been an alarming increase in the prevalence of obesity in people with type 1
diabetes in recent years. Although obesity has long been recognized as a major risk factor …

The importance of interpreting machine learning models for blood glucose prediction in diabetes: an analysis using SHAP

F Prendin, J Pavan, G Cappon, S Del Favero… - Scientific reports, 2023 - nature.com
Abstract Machine learning has become a popular tool for learning models of complex
dynamics from biomedical data. In Type 1 Diabetes (T1D) management, these models are …

Impact of flash glucose monitoring on hypoglycaemia in adults with type 1 diabetes managed with multiple daily injection therapy: a pre-specified subgroup analysis of …

P Oskarsson, R Antuna, P Geelhoed-Duijvestijn… - Diabetologia, 2018 - Springer
Aims/hypothesis Evidence for the effectiveness of interstitial glucose monitoring in
individuals with type 1 diabetes using multiple daily injection (MDI) therapy is limited. In this …

Evidence-informed clinical practice recommendations for treatment of type 1 diabetes complicated by problematic hypoglycemia

P Choudhary, MR Rickels, PA Senior… - Diabetes …, 2015 - Am Diabetes Assoc
Problematic hypoglycemia, defined as two or more episodes per year of severe
hypoglycemia or as one episode associated with impaired awareness of hypoglycemia …