Biomimetic neural scaffolds: a crucial step towards optimal peripheral nerve regeneration

J Du, H Chen, L Qing, X Yang, X Jia - Biomaterials science, 2018 - pubs.rsc.org
Peripheral nerve injury is a common disease that affects more than 20 million people in the
United States alone and remains a major burden to society. The current gold standard …

Xenotransplantation: past, present, and future

B Ekser, P Li, DKC Cooper - Current opinion in organ …, 2017 - journals.lww.com
Xenotransplantation: past, present, and future : Current Opinion in Organ Transplantation
Xenotransplantation: past, present, and future : Current Opinion in Organ Transplantation Log in …

Polymer microcapsules and microbeads as cell carriers for in vivo biomedical applications

B Kupikowska-Stobba, D Lewińska - Biomaterials science, 2020 - pubs.rsc.org
Polymer microcarriers are being extensively explored as cell delivery vehicles in cell-based
therapies and hybrid tissue and organ engineering. Spherical microcarriers are of particular …

[HTML][HTML] Corneal xenotransplantation: Where are we standing?

CH Yoon, HJ Choi, MK Kim - Progress in retinal and eye research, 2021 - Elsevier
The search for alternatives to allotransplants is driven by the shortage of corneal donors and
is demanding because of the limitations of the alternatives. Indeed, current progress in …

Will genetic engineering carry xenotransplantation of pig islets to the clinic?

E Kemter, J Denner, E Wolf - Current diabetes reports, 2018 - Springer
Abstract Purpose of Review Porcine islets represent a potentially attractive beta-cell source
for xenotransplantation into patients with type 1 diabetes, who are not eligible to islet allo …

Current status of porcine islet xenotransplantation

TM Coe, JF Markmann, CG Rickert - Current opinion in organ …, 2020 - journals.lww.com
This review will detail the current status of islet xenotransplantation as a potential treatment
for type I diabetes mellitus, focusing on recent advances in porcine xenogeneic islet …

[HTML][HTML] Neonatal islets from human PD-L1 transgenic pigs reduce immune cell activation and cellular rejection in humanized nonobese diabetic-scid IL2rγnull mice

Y Lei, L Wolf-van Buerck, M Honarpisheh… - American Journal of …, 2024 - Elsevier
Strong xenorejection limits the clinical application of porcine islet transplantation in type 1
diabetes. Targeting T cell-mediated rejection is one of the main approaches to improve long …

[HTML][HTML] Optimal temperature for the long-term culture of adult porcine islets for xenotransplantation

N Sakata, G Yoshimatsu, R Kawakami… - Frontiers in …, 2023 - frontiersin.org
Porcine islet xenotransplantation represents a promising therapy for severe diabetes
mellitus. Long-term culture of porcine islets is a crucial challenge to permit the on-demand …

[HTML][HTML] The role of costimulation blockade in solid organ and islet xenotransplantation

KP Samy, JR Butler, P Li, DKC Cooper… - Journal of immunology …, 2017 - hindawi.com
Pig-to-human xenotransplantation offers a potential bridge to the growing disparity between
patients with end-stage organ failure and graft availability. Early studies attempting to …

Transplantation of macroencapsulated insulin-producing cells

AJ Hwa, GC Weir - Current diabetes reports, 2018 - Springer
Abstract Purpose of Review There is considerable interest in using macroencapsulation
devices as a delivery strategy for transplanting insulin-producing cells. This review aims to …