Hepatic cholesterol transport and its role in non-alcoholic fatty liver disease and atherosclerosis

H Li, XH Yu, X Ou, XP Ouyang, CK Tang - Progress in lipid research, 2021 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a quickly emerging global health problem
representing the most common chronic liver disease in the world. Atherosclerotic …

MicroRNA regulation of atherosclerosis

MW Feinberg, KJ Moore - Circulation research, 2016 - Am Heart Assoc
Atherosclerosis and its attendant clinical complications, such as myocardial infarction,
stroke, and peripheral artery disease, are the leading cause of morbidity and mortality in …

Foam cell formation: A new target for fighting atherosclerosis and cardiovascular disease

EM Maguire, SWA Pearce, Q Xiao - Vascular Pharmacology, 2019 - Elsevier
During atherosclerosis, the gradual accumulation of lipids into the subendothelial space of
damaged arteries results in several lipid modification processes followed by macrophage …

Noncoding RNA s in disease

E Lekka, J Hall - FEBS letters, 2018 - Wiley Online Library
Noncoding RNA s are emerging as potent and multifunctional regulators in all biological
processes. In parallel, a rapidly growing number of studies has unravelled associations …

Non-coding RNAs: the new central dogma of cancer biology

PE Saw, X Xu, J Chen, EW Song - Science China Life Sciences, 2021 - Springer
The central dogma of molecular biology states that the functions of RNA revolve around
protein translation. Until the last decade, most researches were geared towards …

MicroRNAs in metabolism and metabolic disorders

V Rottiers, AM Näär - Nature reviews Molecular cell biology, 2012 - nature.com
MicroRNAs (miRNAs) have recently emerged as key regulators of metabolism. For example,
miR-33a and miR-33b have a crucial role in controlling cholesterol and lipid metabolism in …

The role of the ATP-binding cassette A1 (ABCA1) in human disease

L Jacobo-Albavera, M Domínguez-Pérez… - International journal of …, 2021 - mdpi.com
Cholesterol homeostasis is essential in normal physiology of all cells. One of several
proteins involved in cholesterol homeostasis is the ATP-binding cassette transporter A1 …

Prognostic serum miRNA biomarkers associated with Alzheimer's disease shows concordance with neuropsychological and neuroimaging assessment

L Cheng, JD Doecke, RA Sharples, VL Villemagne… - Molecular …, 2015 - nature.com
There is no consensus for a blood-based test for the early diagnosis of Alzheimer's disease
(AD). Expression profiling of small non-coding RNA's, microRNA (miRNA), has revealed …

The emerging role of microRNAs in Alzheimer's disease

GD Femminella, N Ferrara, G Rengo - Frontiers in physiology, 2015 - frontiersin.org
MicroRNAs (miRNAs) are small non-coding RNA which have been shown to regulate gene
expression. The alteration ofmiRNAs expression has been associated with several …

MicroRNAs in metabolic disease

C Fernández-Hernando, CM Ramírez… - … , and vascular biology, 2013 - Am Heart Assoc
Alterations in the metabolic control of lipid and glucose homeostasis predispose an
individual to develop cardiometabolic diseases, such as type 2-diabetes mellitus and …