Tailoring materials for modulation of macrophage fate
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
The cytoskeleton—a complex interacting meshwork
T Hohmann, F Dehghani - Cells, 2019 - mdpi.com
The cytoskeleton of animal cells is one of the most complicated and functionally versatile
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …
Microglial Piezo1 senses Aβ fibril stiffness to restrict Alzheimer's disease
The pathology of Alzheimer's disease (AD) is featured with extracellular amyloid-β (Aβ)
plaques, whose impact on the mechanical properties of the surrounding brain tissues is …
plaques, whose impact on the mechanical properties of the surrounding brain tissues is …
Actin dynamics, architecture, and mechanics in cell motility
L Blanchoin, R Boujemaa-Paterski… - Physiological …, 2014 - journals.physiology.org
Tight coupling between biochemical and mechanical properties of the actin cytoskeleton
drives a large range of cellular processes including polarity establishment, morphogenesis …
drives a large range of cellular processes including polarity establishment, morphogenesis …
[HTML][HTML] From properties to toxicity: Comparing microplastics to other airborne microparticles
Microplastic (MP) debris is considered as a potentially hazardous material. It is omnipresent
in our environment, and evidence that MP is also abundant in the atmosphere is increasing …
in our environment, and evidence that MP is also abundant in the atmosphere is increasing …
Phagocytosis: receptors, signal integration, and the cytoskeleton
SA Freeman, S Grinstein - Immunological reviews, 2014 - Wiley Online Library
Phagocytosis is a remarkably complex and versatile process: it contributes to innate
immunity through the ingestion and elimination of pathogens, while also being central to …
immunity through the ingestion and elimination of pathogens, while also being central to …
Mechanobiology of macrophages: how physical factors coregulate macrophage plasticity and phagocytosis
N Jain, J Moeller, V Vogel - Annual review of biomedical …, 2019 - annualreviews.org
In addition to their early-recognized functions in host defense and the clearance of apoptotic
cell debris, macrophages play vital roles in tissue development, homeostasis, and repair. If …
cell debris, macrophages play vital roles in tissue development, homeostasis, and repair. If …
[HTML][HTML] Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function
To accommodate the changing needs of the developing brain, microglia must undergo
substantial morphological, phenotypic, and functional reprogramming. Here, we examined …
substantial morphological, phenotypic, and functional reprogramming. Here, we examined …
The cell biology of phagocytosis
RS Flannagan, V Jaumouillé… - Annual Review of …, 2012 - annualreviews.org
Engulfment and destruction of invading microorganisms by phagocytosis are critical
components of the innate immune response. In addition, phagocytosis is also required for …
components of the innate immune response. In addition, phagocytosis is also required for …
Filopodia: molecular architecture and cellular functions
PK Mattila, P Lappalainen - Nature reviews Molecular cell biology, 2008 - nature.com
Filopodia are thin, actin-rich plasma-membrane protrusions that function as antennae for
cells to probe their environment. Consequently, filopodia have an important role in cell …
cells to probe their environment. Consequently, filopodia have an important role in cell …