Abnormalities of membrane function and lipid metabolism in hypertension: a review

J Zicha, J Kuneš, MA Devynck - American Journal of …, 1999 - academic.oup.com
Hypertension, which is characterized by multiple alterations in the structure and function of
the cell membrane, is often associated with important metabolic abnormalities including …

Augmented reality in spine surgery–past, present, and future

TD Azad, A Warman, JA Tracz, LP Hughes, BF Judy… - The Spine Journal, 2024 - Elsevier
Abstract BACKGROUND CONTEXT Augmented reality (AR) is increasingly recognized as a
valuable tool in spine surgery. Here we provides an overview of the key developments and …

Effect of the flavanolignans of Silybum marianum L. on lipid peroxidation in rat liver microsomes and freshly isolated hepatocytes

E Bosisio, C Benelli, O Pirola - Pharmacological Research, 1992 - Elsevier
The effect of several flavanolignans (silicristin, silidianin, silybin and isosilybin) present in
silymarin, the extract of Silybum marianum fruits, was tested on lipid peroxidation in rat liver …

p90RSK is a serum-stimulated Na+/H+ exchanger isoform-1 kinase: regulatory phosphorylation of serine 703 of Na+/H+ exchanger isoform-1

E Takahashi, J Abe, B Gallis, R Aebersold… - Journal of Biological …, 1999 - ASBMB
The Na+/H+ exchanger isoform-1 (NHE-1) is the key member of a family of exchangers that
regulates intracellular pH and cell volume. Activation of NHE-1 by growth factors is rapid …

Differentiated properties and proliferation of arterial smooth muscle cells in culture

J Thyberg - International review of cytology, 1996 - Elsevier
The smooth muscle cell is the sole cell type normally found in the media of mammalian
arteries. In the adult, it is a terminally differentiated cell that expresses cytoskeletal marker …

The renin-angiotensin system and vascular hypertrophy

C Rosendorff - Journal of the American College of Cardiology, 1996 - jacc.org
In addition to its vasoconstrictor and aldosterone-stimulating action, angiotensin II also
drives cell growth and replication in the cardiovascular system, which may result in …

Role of ion channels and exchangers in mechanical stretch–induced cardiomyocyte hypertrophy

T Yamazaki, I Komuro, S Kudoh, Y Zou… - Circulation …, 1998 - Am Heart Assoc
We have previously reported that stretching of cardiomyocytes activates the phosphorylation
cascade of protein kinases, including Raf-1 kinase and mitogen-activated protein (MAP) …

14-3-3 Binding to Na+/H+ exchanger isoform-1 is associated with serum-dependent activation of Na+/H+ exchange

S Lehoux, J Abe, JA Florian, BC Berk - Journal of Biological Chemistry, 2001 - ASBMB
Na+/H+ exchanger isoform-1 (NHE1), the ubiquitous form of the Na+/H+ exchanger, has
increased activity in hypertensive patients and in animal models of hypertension …

p38 Kinase Is a Negative Regulator of Angiotensin II Signal Transduction in Vascular Smooth Muscle Cells: Effects on Na+/H+ Exchange and ERK1/2

M Kusuhara, E Takahashi, TE Peterson, J Abe… - Circulation …, 1998 - Am Heart Assoc
Activation of the Na+/H+ exchanger isoform-1 (NHE-1) by angiotensin II is an early signal
transduction event that may regulate vascular smooth muscle cell (VSMC) growth and …

Regulation of ion pumps and carriers in vascular smooth muscle

ME O'Donnell, NE Owen - Physiological reviews, 1994 - journals.physiology.org
The intent of this review is to provide an overview of pump-and carrier-mediated ion
transport processes known to be present in vascular smooth muscle cells. These ion pumps …