Exercise training maintains cardiovascular health: signaling pathways involved and potential therapeutics
Exercise training has been widely recognized as a healthy lifestyle as well as an effective
non-drug therapeutic strategy for cardiovascular diseases (CVD). Functional and …
non-drug therapeutic strategy for cardiovascular diseases (CVD). Functional and …
Molecular mechanisms underlying cardiac adaptation to exercise
Exercise elicits coordinated multi-organ responses including skeletal muscle, vasculature,
heart, and lung. In the short term, the output of the heart increases to meet the demand of …
heart, and lung. In the short term, the output of the heart increases to meet the demand of …
miR-222 is necessary for exercise-induced cardiac growth and protects against pathological cardiac remodeling
Exercise induces physiological cardiac growth and protects the heart against pathological
remodeling. Recent work suggests exercise also enhances the heart's capacity for repair …
remodeling. Recent work suggests exercise also enhances the heart's capacity for repair …
The miR-29 family: genomics, cell biology, and relevance to renal and cardiovascular injury
AJ Kriegel, Y Liu, Y Fang, X Ding… - Physiological …, 2012 - journals.physiology.org
The human miR-29 family of microRNAs has three mature members, miR-29a, miR-29b, and
miR-29c. miR-29s are encoded by two gene clusters. Binding sites for several transcriptional …
miR-29c. miR-29s are encoded by two gene clusters. Binding sites for several transcriptional …
Circulating miR-29a, among other up-regulated microRNAs, is the only biomarker for both hypertrophy and fibrosis in patients with hypertrophic cardiomyopathy
Objectives: The purpose of this paper was to determine whether microRNAs (miRNAs)
involved in myocardial remodeling were differentially expressed in the blood of hypertrophic …
involved in myocardial remodeling were differentially expressed in the blood of hypertrophic …
Molecular mechanisms of cardiac remodeling and regeneration in physical exercise
D Schüttler, S Clauss, LT Weckbach, S Brunner - Cells, 2019 - mdpi.com
Regular physical activity with aerobic and muscle-strengthening training protects against the
occurrence and progression of cardiovascular disease and can improve cardiac function in …
occurrence and progression of cardiovascular disease and can improve cardiac function in …
Role of exercise in the prevention of cardiovascular disease: results, mechanisms, and new perspectives
G Schuler, V Adams, Y Goto - European heart journal, 2013 - academic.oup.com
On an empirical basis, exercise has been regarded as a fundamental pre-requisite for
human well-being and physical integrity since classical times. Only in the last decades …
human well-being and physical integrity since classical times. Only in the last decades …
Physiological cardiac remodelling in response to endurance exercise training: cellular and molecular mechanisms
GM Ellison, CD Waring, C Vicinanza, D Torella - Heart, 2012 - heart.bmj.com
Exercise training fosters the health and performance of the cardiovascular system, and
represents nowadays a powerful tool for cardiovascular therapy. Exercise exerts its …
represents nowadays a powerful tool for cardiovascular therapy. Exercise exerts its …
Rapid upregulation and clearance of distinct circulating microRNAs after prolonged aerobic exercise
AL Baggish, J Park, PK Min, S Isaacs… - Journal of applied …, 2014 - journals.physiology.org
Short nonprotein coding RNA molecules, known as microRNAs (miRNAs), are intracellular
mediators of adaptive processes, including muscle hypertrophy, contractile force generation …
mediators of adaptive processes, including muscle hypertrophy, contractile force generation …
Noncoding RNAs in cardiovascular disease: current knowledge, tools and technologies for investigation, and future directions: a scientific statement from the american …
Background: The discovery that much of the non–protein-coding genome is transcribed and
plays a diverse functional role in fundamental cellular processes has led to an explosion in …
plays a diverse functional role in fundamental cellular processes has led to an explosion in …