Compared to terrestrial animals, fish have to cope with more-challenging osmotic and ionic
gradients from aquatic environments with diverse salinities, ion compositions, and pH …

Extracellular acid can have important effects on neuron function. In central and peripheral
neurons, acid-sensing ion channels (ASICs) have emerged as key receptors for extracellular …

Acid-sensing ion channels (ASICs) are ligand-gated ion channels that are exquisitely
sensitive to extracellular protons and can sense transient as well as sustained acidification …

The neural crest is an evolutionary novelty that fostered the emergence of vertebrate
anatomical innovations such as the cranium and jaws. During embryonic development …

Acid-sensing ion channels (ASICs) are H+-gated Na+ channels, which are present in most, if
not all, neurons. The typical ASIC current is transient and is elicited by a rapid drop in the …

Transepithelial transport is one of the major processes involved in the mechanism of
homeostasis of body fluids in vertebrates including fish. The current models of ion regulation …

Acid-sensing ion channels (ASICs) are Na+ channels gated by extracellular H+. Six ASIC
subunits that are expressed in neurons have been characterized. The tarantula toxin …

The acid‐sensing ion channels (ASICs) and epithelial sodium channels (ENaC) are
members of a superfamily of channels that play critical roles in mechanosensation …

Acid-sensing ion channels (ASICs) are H+-gated members of the degenerin/epithelial Na+
channel (DEG/ENaC) family in vertebrate neurons. Several ASICs are expressed in sensory …

Acid-sensing ion channels are ligand-gated cation channels, gated by extracellular H+. H+
is the simplest ligand possible, and whereas for larger ligands that gate ion channels …