Are we close to defining a metabolomic signature of human obesity? A systematic review of metabolomics studies

OD Rangel-Huerta, B Pastor-Villaescusa, A Gil - Metabolomics, 2019 - Springer
Introduction Obesity is a disorder characterized by a disproportionate increase in body
weight in relation to height, mainly due to the accumulation of fat, and is considered a …

Seaweed components as potential modulators of the gut microbiota

E Shannon, M Conlon, M Hayes - Marine Drugs, 2021 - mdpi.com
Macroalgae, or seaweeds, are a rich source of components which may exert beneficial
effects on the mammalian gut microbiota through the enhancement of bacterial diversity and …

Brown macroalgae as valuable food ingredients

NC Afonso, MD Catarino, AMS Silva, SM Cardoso - Antioxidants, 2019 - mdpi.com
Due to the balanced nutritional value and abundance of bioactive compounds, seaweeds
represent great candidates to be used as health-promoting ingredients by the food industry …

Bioactive properties of marine phenolics

R Mateos, JR Pérez-Correa, H Domínguez - Marine drugs, 2020 - mdpi.com
Phenolic compounds from marine organisms are far less studied than those from terrestrial
sources since their structural diversity and variability require powerful analytical tools …

Phlorotannins: A review of extraction methods, structural characteristics, bioactivities, bioavailability, and future trends

W Meng, T Mu, H Sun, M Garcia-Vaquero - Algal Research, 2021 - Elsevier
Background In recent years, phlorotannins, a class of polyphenols with strong biological
properties derived from brown algae and not present in terrestrial organisms, have attracted …

Seaweed secondary metabolites with beneficial health effects: An overview of successes in in vivo studies and clinical trials

GP Rosa, WR Tavares, PMC Sousa, AK Pagès… - Marine drugs, 2019 - mdpi.com
Macroalgae are increasingly viewed as a source of secondary metabolites with great
potential for the development of new drugs. In this development, in vitro studies are only the …

A bioactive substance derived from brown seaweeds: Phlorotannins

H Zheng, Y Zhao, L Guo - Marine Drugs, 2022 - mdpi.com
Phlorotannins are a type of natural active substance extracted from brown algae, which
belong to a type of important plant polyphenol. Phloroglucinol is the basic unit in its …

Low-molecular weight metabolites from polyphenols as effectors for attenuating neuroinflammation

D Carregosa, R Carecho, I Figueira… - Journal of agricultural …, 2019 - ACS Publications
Age-associated pathophysiological changes such as neurodegenerative diseases are
multifactorial conditions with increasing incidence and no existing cure. The possibility of …

Polyphenols: A route from bioavailability to bioactivity addressing potential health benefits to tackle human chronic diseases

S Vivarelli, C Costa, M Teodoro, F Giambò… - Archives of …, 2023 - Springer
Chronic pathologies or non-communicable diseases (NCDs) include cardiovascular
diseases, metabolic syndrome, neurological diseases, respiratory disorders and cancer …

Phlorotannins: From isolation and structural characterization, to the evaluation of their antidiabetic and anticancer potential

F Erpel, R Mateos, J Pérez-Jiménez… - Food Research …, 2020 - Elsevier
Phlorotannins are phenolic characteristic compounds of brown seaweeds that are only
constituted by phloroglucinol (1, 3, 5-trihydroxybenzene). They are chain-and net-like …