Deprescribing for community-dwelling older adults: a systematic review and meta-analysis

HE Bloomfield, N Greer, AM Linsky, J Bolduc… - Journal of general …, 2020 - Springer
Background Polypharmacy and use of inappropriate medications have been linked to
increased risk of falls, hospitalizations, cognitive impairment, and death. The primary …

Clinical consequences of polypharmacy in elderly

RL Maher, J Hanlon, ER Hajjar - Expert opinion on drug safety, 2014 - Taylor & Francis
Introduction: Polypharmacy, defined as the use of multiple drugs or more than are medically
necessary, is a growing concern for older adults. MEDLINE and EMBASE databases were …

Polypharmacy, hospitalization, and mortality risk: a nationwide cohort study

TI Chang, H Park, DW Kim, EK Jeon, CM Rhee… - Scientific reports, 2020 - nature.com
Polypharmacy is a growing and major public health issue, particularly in the geriatric
population. This study aimed to examine the association between polypharmacy and the risk …

Effect of a pharmacist-led educational intervention on inappropriate medication prescriptions in older adults: the D-PRESCRIBE randomized clinical trial

P Martin, R Tamblyn, A Benedetti, S Ahmed… - Jama, 2018 - jamanetwork.com
Importance High rates of inappropriate prescribing persist among older adults in many
outpatient settings, increasing the risk of adverse drug events and drug-related …

The feasibility and effect of deprescribing in older adults on mortality and health: a systematic review and meta‐analysis

AT Page, RM Clifford, K Potter… - British journal of …, 2016 - Wiley Online Library
Aims Deprescribing is a suggested intervention to reverse the potential iatrogenic harms of
inappropriate polypharmacy. The review aimed to determine whether or not deprescribing is …

Health outcomes associated with polypharmacy in community‐dwelling older adults: a systematic review

TR Fried, J O'Leary, V Towle… - Journal of the …, 2014 - Wiley Online Library
Objectives To summarize evidence regarding the health outcomes associated with
polypharmacy, defined as number of prescribed medications, in older community‐dwelling …

Interventions to improve the appropriate use of polypharmacy for older people

A Rankin, CA Cadogan, SM Patterson… - Cochrane Database …, 2018 - cochranelibrary.com
Background Inappropriate polypharmacy is a particular concern in older people and is
associated with negative health outcomes. Choosing the best interventions to improve …

Interventions to improve the appropriate use of polypharmacy in older people: a Cochrane systematic review

JA Cooper, CA Cadogan, SM Patterson, N Kerse… - BMJ open, 2015 - bmjopen.bmj.com
Objective To summarise the findings of an updated Cochrane review of interventions aimed
at improving the appropriate use of polypharmacy in older people. Design Cochrane …

Medication therapy management interventions in outpatient settings: a systematic review and meta-analysis

M Viswanathan, LC Kahwati, CE Golin… - JAMA internal …, 2015 - jamanetwork.com
Importance Medication therapy management (MTM) services (also calledclinical pharmacy
services) aim to reduce medication-related problems and their downstream outcomes …

Audit and feedback: effects on professional practice and healthcare outcomes

N Ivers, G Jamtvedt, S Flottorp… - Cochrane database …, 2012 - cochranelibrary.com
Background Audit and feedback is widely used as a strategy to improve professional
practice either on its own or as a component of multifaceted quality improvement …