[HTML][HTML] Cell fusion as a link between the SARS-CoV-2 spike protein, COVID-19 complications, and vaccine side effects

Y Lazebnik - Oncotarget, 2021 - ncbi.nlm.nih.gov
A distinctive feature of the SARS-CoV-2 spike protein is its ability to efficiently fuse cells, thus
producing syncytia found in COVID-19 patients. This commentary proposes how this ability …

Making it stick: chasing the optimal stem cells for cardiac regeneration

P Quijada, MA Sussman - Expert review of cardiovascular therapy, 2014 - Taylor & Francis
Despite the increasing use of stem cells for regenerative-based cardiac therapy, the optimal
stem cell population (s) remains in a cloud of uncertainty. In the past decade, the field has …

[HTML][HTML] Distinct DNA-based epigenetic switches trigger transcriptional activation of silent genes in human dermal fibroblasts

GN Pandian, J Taniguchi, S Junetha, S Sato, L Han… - Scientific reports, 2014 - nature.com
The influential role of the epigenome in orchestrating genome-wide transcriptional activation
instigates the demand for the artificial genetic switches with distinct DNA sequence …

[HTML][HTML] Cell-cell fusion as a mechanism of DNA exchange in cancer

SC Searles, EK Santosa, JD Bui - Oncotarget, 2018 - ncbi.nlm.nih.gov
Cell-cell fusion describes the process by which two cells combine their plasma membranes
and become a single cell, possessing and retaining certain genetic information from each …

Tracking fusion of human mesenchymal stem cells after transplantation to the heart

BT Freeman, NA Kouris, BM Ogle - Stem cells translational …, 2015 - academic.oup.com
Evidence suggests that transplanted mesenchymal stem cells (MSCs) can aid recovery of
damaged myocardium caused by myocardial infarction. One possible mechanism for MSC …

[HTML][HTML] Fusion between hematopoietic and epithelial cells in adult human intestine

AD Silk, CE Gast, PS Davies, FD Fakhari… - PLoS …, 2013 - journals.plos.org
Following transplantation of hematopoietic lineage cells, genetic markers unique to the
transplanted cells have been detected in non-hematopoietic recipient cells of human liver …

The shock of being united and symphiliosis: Another lesson from plants?

Y Lazebnik - Cell Cycle, 2014 - Taylor & Francis
A common view is that an accidental increase in ploidy contributes to the evolution of
neoplastic cells primarily by decreasing the fidelity of mitosis with extra chromosomes and …

[HTML][HTML] The problem of colliding networks and its relation to cell fusion and cancer

AA Koulakov, Y Lazebnik - Biophysical journal, 2012 - cell.com
Cell fusion, a process that merges two or more cells into one, is required for normal
development and has been explored as a tool for stem cell therapy. It has also been …

[HTML][HTML] JMJD3 aids in reprogramming of bone marrow progenitor cells to hepatic phenotype through epigenetic activation of hepatic transcription factors

V Kochat, Z Equbal, P Baligar, V Kumar, M Srivastava… - PLoS …, 2017 - journals.plos.org
The strictly regulated unidirectional differentiation program in some somatic stem/progenitor
cells has been found to be modified in the ectopic site (tissue) undergoing regeneration. In …

Injured hepatocyte-released microvesicles induce bone marrow-derived mononuclear cells differentiation

L Simon, M López, C Uribe-Cruz, DFP Vergara, L Silla… - Differentiation, 2015 - Elsevier
The ability of bone marrow-derived mononuclear cells (BMMCs) to differentiate into
hepatocyte-like cells under different conditions has been demonstrated previously. In the …