Free radical properties, source and targets, antioxidant consumption and health

G Martemucci, C Costagliola, M Mariano, L D'andrea… - Oxygen, 2022 - mdpi.com
Free radicals have acquired growing importance in the fields of biology and medicine. They
are produced during many different endogenous and exogenous processes. Mitochondria …

Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Chemical Biology of H2S Signaling through Persulfidation

MR Filipovic, J Zivanovic, B Alvarez… - Chemical …, 2018 - ACS Publications
Signaling by H2S is proposed to occur via persulfidation, a posttranslational modification of
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …

A review of hydrogen sulfide synthesis, metabolism, and measurement: is modulation of hydrogen sulfide a novel therapeutic for cancer?

X Cao, L Ding, Z Xie, Y Yang, M Whiteman… - Antioxidants & redox …, 2019 - liebertpub.com
Abstract Significance: Hydrogen sulfide (H2S) has been recognized as the third gaseous
transmitter alongside nitric oxide and carbon monoxide. In the past decade, numerous …

Pathophysiology and therapeutic perspectives of oxidative stress and neurodegenerative diseases: a narrative review

M Rekatsina, A Paladini, A Piroli, P Zis, JV Pergolizzi… - Advances in …, 2020 - Springer
Introduction Neurodegeneration is the term describing the death of neurons both in the
central nervous system and periphery. When affecting the central nervous system, it is …

Hydrogen sulfide (H2S) signaling in plant development and stress responses

H Liu, J Wang, J Liu, T Liu, S Xue - Abiotech, 2021 - Springer
Hydrogen sulfide (H 2 S) was initially recognized as a toxic gas and its biological functions
in mammalian cells have been gradually discovered during the past decades. In the latest …

Hydrogen sulfide biology and its role in cancer

S Khattak, MA Rauf, NH Khan, QQ Zhang, HJ Chen… - Molecules, 2022 - mdpi.com
Hydrogen sulfide (H2S) is an endogenous biologically active gas produced in mammalian
tissues. It plays a very critical role in many pathophysiological processes in the body. It can …

H2S-Induced Sulfhydration: Biological Function and Detection Methodology

D Zhang, J Du, C Tang, Y Huang, H Jin - Frontiers in pharmacology, 2017 - frontiersin.org
At appropriate concentrations, hydrogen sulfide, a well-known gasotransmitter, plays
important roles in both physiology and pathophysiology. Increasing evidence suggests that …

[HTML][HTML] Effects of methionine intake on cognitive function in mild cognitive impairment patients and APP/PS1 Alzheimer's Disease model mice: Role of the …

Y Xi, Y Zhang, Y Zhou, Q Liu, X Chen, X Liu, T Grune… - Redox Biology, 2023 - Elsevier
As a dietary intervention, methionine restriction (MR) has been reported to increase
longevity and improve metabolism disorders. However, the effects of MR on alleviating …

Protein persulfidation: Rewiring the hydrogen sulfide signaling in cell stress response

B He, Z Zhang, Z Huang, X Duan, Y Wang, J Cao… - Biochemical …, 2023 - Elsevier
The past few decades have witnessed significant progress in the discovery of hydrogen
sulfide (H 2 S) as a ubiquitous gaseous signaling molecule in mammalian physiology, akin …