Sex-dependent fear memory impairment in cocaine-sired rat offspring

MT Rich, SJ Worobey, S Mankame, ZP Pang… - Science …, 2023 - science.org
Cocaine self-administration by male rats results in neuronal and behavioral alterations in
offspring, including responses to cocaine. Given the high degree of overlap between the …

Sex difference affects fear extinction but not lithium efficacy in rats following fear-conditioning with respect to the hippocampal level of BDNF

M Rahimi-Danesh, MA Samizadeh, AE Sajadi… - Pharmacology …, 2024 - Elsevier
In rodents, exposure to electrical shock and creating a strong fear memory using fear-
conditioning model can induce PTSD-like behavior. In this study, we induced a fear …

Impact of mephedrone on fear memory in adolescent rats: Involvement of matrix Metalloproteinase-9 (MMP-9) and N-Methyl-D-aspartate (NMDA) receptor

P Grochecki, I Smaga, K Wydra… - International Journal of …, 2023 - mdpi.com
Treatment of Post-Traumatic Stress Disorder (PTSD) is complicated by the presence of drug
use disorder comorbidity. Here, we examine whether conditioned fear (PTSD model) …

Repeated ethanol exposure following avoidance conditioning impairs avoidance extinction and modifies conditioning‐associated prefrontal dendritic changes in a …

A Lguensat, Z Boudjafad, E Giorla… - European Journal of …, 2021 - Wiley Online Library
Abstract Treatment of post‐traumatic stress disorder is complicated by the presence of
alcohol use disorder comorbidity. Little is known about the underlying brain mechanisms …

Alterations in Neuronal Excitability and Spatial Memory Due to PTSD: Insights from a Murine Model

Y Shi, Y Sun, X Li, X Zhao, Z Chen, D Liu - Available at SSRN 4755274 - papers.ssrn.com
This study aimed to explore the implications of post-traumatic stress disorder (PTSD) on the
action potential patterns and properties of neurons in the basolateral amygdala (BLA) and …

Investigating the Bidirectional Relationship between Cocaine-Induced Locomotor Sensitization and Posttraumatic Stress Disorder-Like in Dba/2j Mice

T Matonda-ma-Nzuzi, V Didone, L Godefroid… - Available at SSRN … - papers.ssrn.com
To date, the relationship between cocaine use disorder and posttraumatic stress disorder
(PTSD) remains poorly understood. A few animal studies reported evidence that PTSD-like …