Glycosphingolipids (GSLs) are major amphiphilic glycolipids present on the surface of living
cell membranes. They have important biological functions, including maintaining plasma …

Sphingolipids containing acyl residues that are hydroxylated at C-2 are found in most, if not
all, eukaryotes and certain bacteria. 2-hydroxylated sphingolipids are present in many …

As ageing is a major risk factor for the development of non-communicable diseases,
extending healthspan has become a medical and societal necessity. Precise lipid …

The sea cucumber phospholipids (SC-PLs) are involved in regulating multiple chronic lipid
metabolism disorders, but their mechanism remains unknown. Herein, ethanol diet-induced …

Great advances in lipidomics during the last years have opened the door to a broader
knowledge of oxygenated lipids. These substances are derived either from the inclusion of …

Aims To evaluate abnormal metabolites related to treatment response and prognosis of
multiple myeloma (MM) patients through ultra performance liquid chromatography tandem …

Purpose Cholangiocarcinoma (CCA) is a malignancy arising from the bile duct epithelium
and has a poor outcome. Sulfatides are lipid components of lipid rafts, and are implicated in …

Cholangiocarcinoma (CCA) is an aggressive tumor of the biliary epithelium with poor
survival that shows limited response to conventional chemotherapy. Increased expression of …

Objective To investigate the expression of glycosphingolipids in serum and tissue from
patients with cholangiocarcinoma compared with healthy controls. Methods Nanospray …

Oleic acid (OA), one of the most important monounsaturated fatty acids, possesses
protective properties against chronic liver disease (CLD) development, but the underlying …