Low and oscillatory wall shear stress is widely assumed to play a key role in the initiation
and development of atherosclerosis. Indeed, some studies have relied on the low shear …

Cumulative evidence from histology-based studies demonstrate that the currently available
intravascular imaging techniques have fundamental limitations that do not allow complete …

Expert recommendations on the assessment of wall shear stress in human coronary arteries:
existing methodologies, technical considerations, and clinical applications | European Heart …

Coronary computed tomographic angiography (CCTA) is a non-invasive imaging modality
for the visualization of the heart and coronary arteries. To fully exploit the potential of the …

Hemodynamic factors, induced by pulsatile blood flow, play a crucial role in vascular health
and diseases, such as the initiation and progression of atherosclerosis. Computational fluid …

Rupture of atherosclerotic plaques causing thrombosis is the main cause of acute coronary
syndrome and ischemic strokes. Inhibition of thrombosis is one of the important tasks …

The role of low and oscillating shear stress as a key factor for localizing early atherosclerotic
plaques is generally accepted. Once more advanced plaques protrude into the lumen, the …

BACKGROUND: Plaque composition and wall shear stress (WSS) magnitude act as well-
established players in coronary plaque progression. However, WSS magnitude per se does …

Wall shear stress (WSS), the frictional force of the blood on the vessel wall, plays a crucial
role in atherosclerotic plaque development. Low WSS has been associated with plaque …

Aims: To develop and validate a new methodology that allows accurate 3-dimensional (3-D)
coronary artery reconstruction using standard, simple angiographic and intravascular …