Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …

In the past period, due to the rapid development of next-generation sequencing technology,
accumulating evidence has clarified the complex role of the human microbiota in the …

Pseudomonas aeruginosa is one of the most virulent opportunistic Gram-negative bacterial
pathogens in humans. It causes many acute and chronic infections with morbidity and …

Targeted therapy and immunotherapy have brought hopes for precision cancer treatment.
However, complex physiological barriers and tumor immunosuppression result in poor …

Infection is a major co-morbidity that contributes to impaired healing in diabetic wounds.
Although impairments in diabetic neutrophils have been blamed for this co-morbidity, what …

Abstract Type 3 Secretion System (T3SS) is a highly conserved virulence structure that plays
an essential role in the pathogenesis of many Gram-negative pathogenic bacteria, including …

Hepatocellular carcinoma (HCC) is one of the high-metastatic types of cancer, and
metastasis occurs in one-third of patients with HCC. To maintain the effectiveness of drug …

The incidence and mortality of lung cancer are on the rise worldwide. However, the benefit
of clinical treatment in lung cancer is limited. Owning to important sources of drug …

Despite many preventive measures, including prophylactic antibiotics, periprosthetic joint
infection (PJI) remains a devastating complication following arthroplasty, leading to pain …

Cancer presents a formidable challenge in modern medicine due to the intratumoral
heterogeneity and the dynamic microenvironmental niche. Natural or genetically engineered …