As early as the 1920s, and subsequently in the 1959 Build and Blood Pressure Study (S1. 5-
1) of almost 5 million adults insured between 1934 and 1954, a strong direct relationship …

An adrenal incidentaloma is now established as a common endocrine diagnosis that
requires a multidisciplinary approach for effective management. The majority of patients can …

Primary aldosteronism is a common cause of hypertension and is a risk factor for
cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …

Primary aldosteronism is characterized by aldosterone secretion that is independent of renin
and angiotensin II and sodium status. The deleterious effects of primary aldosteronism are …

Abstract Background A total of 44.7% adults in China have hypertension, but the prevalence
of primary aldosteronism (PA) in Chinese hypertensive patients is unknown. Objectives This …

We are witnessing a revolution in our understanding of primary aldosteronism (PA). In the
past 2 decades, we have learned that PA is a highly prevalent syndrome that is largely …

Objective: Our objective was to develop clinical practice guidelines for the diagnosis and
treatment of patients with primary aldosteronism. Participants: The Task Force comprised a …

Objectives: We prospectively investigated the prevalence of curable forms of primary
aldosteronism (PA) in newly diagnosed hypertensive patients. Background: The prevalence …

Lifelong therapy with mineralocorticoid receptor antagonists (MRAs) or surgical
adrenalectomy are the recommended treatments for primary aldosteronism (PA). Whether …

Context: In patients who seek surgical cure of primary aldosteronism (PA), The Endocrine
Society Guidelines recommend the use of adrenal vein sampling (AVS), which is invasive …