Insulin‐sensitising drugs (metformin, rosiglitazone, pioglitazone, D‐chiro‐inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility
Background Polycystic ovary syndrome (PCOS) is characterised by infrequent or absent
ovulation, and high levels of androgens and insulin (hyperinsulinaemia). Hyperinsulinaemia …
ovulation, and high levels of androgens and insulin (hyperinsulinaemia). Hyperinsulinaemia …
Obesity and reproductive disorders in women
R Pasquali, C Pelusi, S Genghini… - Human reproduction …, 2003 - academic.oup.com
Obesity, particularly the abdominal phenotype, is associated with several reproductive
disturbances. Whereas mechanisms by which obesity affect fertility are complex and still not …
disturbances. Whereas mechanisms by which obesity affect fertility are complex and still not …
Polycystic ovarian syndrome: diagnosis and management
MT Sheehan - Clinical Medicine & Research, 2004 - Marshfield Clinic
Polycystic ovarian syndrome (PCOS) affects 4% to 12% of women of reproductive age. The
lack of well-defined diagnostic criteria makes identification of this common disease …
lack of well-defined diagnostic criteria makes identification of this common disease …
Metformin: new understandings, new uses
RS Hundal, SE Inzucchi - Drugs, 2003 - Springer
Metformin, a biguanide, has been available in the US for the treatment of type 2 diabetes
mellitus for nearly 8 years. Over this period of time, it has become the most widely prescribed …
mellitus for nearly 8 years. Over this period of time, it has become the most widely prescribed …
Insulin-lowering agents in the management of polycystic ovary syndrome
V De Leo, A La Marca, F Petraglia - Endocrine reviews, 2003 - academic.oup.com
Polycystic ovary syndrome (PCOS) is a medical condition that has brought multiple
specialists together. Gynecologists, endocrinologists, cardiologists, pediatricians, and …
specialists together. Gynecologists, endocrinologists, cardiologists, pediatricians, and …
Serum anti-Müllerian hormone levels remain high until late reproductive age and decrease during metformin therapy in women with polycystic ovary syndrome
T Piltonen, L Morin-Papunen, R Koivunen… - Human …, 2005 - academic.oup.com
BACKGROUND: Anti-Müllerian hormone (AMH) is secreted by granulosa cells of ovarian
early developing follicles and its serum levels have been shown to correlate with small …
early developing follicles and its serum levels have been shown to correlate with small …
[HTML][HTML] Metformin increases the ovulatory rate and pregnancy rate from clomiphene citrate in patients with polycystic ovary syndrome who are resistant to clomiphene …
DT Vandermolen, VS Ratts, WS Evans, DW Stovall… - Fertility and sterility, 2001 - Elsevier
Objective: To determine whether metformin treatment increases the ovulation and
pregnancy rates in response to clomiphene citrate (CC) in women who are resistant to CC …
pregnancy rates in response to clomiphene citrate (CC) in women who are resistant to CC …
[HTML][HTML] D-chiro-inositol induces ovulation in non-polycystic ovary syndrome (PCOS), non-insulin-resistant young women, likely by modulating aromatase expression …
MSB Espinola, AS Laganà, G Bilotta… - The American Journal …, 2021 - ncbi.nlm.nih.gov
Objective: Unknown etiology Background: Anovulation consists in the lack of oocyte release
during the menstrual cycle, leading to an irregular menstrual cycle. Untreated chronic …
during the menstrual cycle, leading to an irregular menstrual cycle. Untreated chronic …
[HTML][HTML] Effects of metformin and rosiglitazone, alone and in combination, in nonobese women with polycystic ovary syndrome and normal indices of insulin sensitivity
JP Baillargeon, DJ Jakubowicz, MJ Iuorno… - Fertility and sterility, 2004 - Elsevier
OBJECTIVE: To determine whether insulin-sensitizing drugs would improve ovulation and T
levels in women with polycystic ovary syndrome (PCOS), without clinical or biochemical …
levels in women with polycystic ovary syndrome (PCOS), without clinical or biochemical …
Descriptive review of the evidence for the use of metformin in polycystic ovary syndrome
Use of metformin in polycystic ovary syndrome (PCOS) is becoming increasingly accepted
and widespread, but clinical practice is ahead of the evidence. Although a wide range of …
and widespread, but clinical practice is ahead of the evidence. Although a wide range of …