Neuronal lipid metabolism: multiple pathways driving functional outcomes in health and disease
TJ Tracey, FJ Steyn, EJ Wolvetang… - Frontiers in molecular …, 2018 - frontiersin.org
Lipids are a fundamental class of organic molecules implicated in a wide range of biological
processes related to their structural diversity, and based on this can be broadly classified …
processes related to their structural diversity, and based on this can be broadly classified …
[HTML][HTML] Amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is an idiopathic, fatal neurodegenerative disease of the
human motor system. In this Seminar, we summarise current concepts about the origin of the …
human motor system. In this Seminar, we summarise current concepts about the origin of the …
Clinical spectrum of amyotrophic lateral sclerosis (ALS)
Amyotrophic lateral sclerosis (ALS) is primarily characterized by progressive loss of motor
neurons, although there is marked phenotypic heterogeneity between cases. Typical, or …
neurons, although there is marked phenotypic heterogeneity between cases. Typical, or …
Effect of high‐caloric nutrition on survival in amyotrophic lateral sclerosis
AC Ludolph, J Dorst, J Dreyhaupt… - Annals of …, 2020 - Wiley Online Library
Objective Weight loss has been identified as a negative prognostic factor in amyotrophic
lateral sclerosis, but there is no evidence regarding whether a high‐caloric diet increases …
lateral sclerosis, but there is no evidence regarding whether a high‐caloric diet increases …
Hypermetabolism in ALS is associated with greater functional decline and shorter survival
Objective To determine the prevalence of hypermetabolism, relative to body composition, in
amyotrophic lateral sclerosis (ALS) and its relationship with clinical features of disease and …
amyotrophic lateral sclerosis (ALS) and its relationship with clinical features of disease and …
Nutritional and metabolic factors in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease that is
classically thought to impact the motor system. Over the past 20 years, research has started …
classically thought to impact the motor system. Over the past 20 years, research has started …
Energy metabolism in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is characterised by the progressive degeneration of
upper and lower motor neurons. Besides motor neuron degeneration, ALS is associated …
upper and lower motor neurons. Besides motor neuron degeneration, ALS is associated …
Dyslipidemia is a protective factor in amyotrophic lateral sclerosis
L Dupuis, P Corcia, A Fergani… - Neurology, 2008 - AAN Enterprises
Background: Amyotrophic lateral sclerosis (ALS) is the most serious form of degenerative
motor neuron disease in adults, characterized by upper and lower motor neuron …
motor neuron disease in adults, characterized by upper and lower motor neuron …
ALS: A bucket of genes, environment, metabolism and unknown ingredients
M Zufiria, FJ Gil-Bea, R Fernandez-Torron… - Progress in …, 2016 - Elsevier
The scientific scenario of amyotrophic lateral sclerosis (ALS) has dramatically changed
since TDP-43 aggregates were discovered in 2006 as the main component of the neuronal …
since TDP-43 aggregates were discovered in 2006 as the main component of the neuronal …
Body mass index, not dyslipidemia, is an independent predictor of survival in amyotrophic lateral sclerosis
Introduction: Recent studies have provided conflicting data regarding the role of
dyslipidemia in amyotrophic lateral sclerosis (ALS). The aim of this study was to determine …
dyslipidemia in amyotrophic lateral sclerosis (ALS). The aim of this study was to determine …