The nuclear factor κB or NF-κB transcription factor family plays a key role in several cellular
functions, ie inflammation, apoptosis, cell survival, proliferation, angiogenesis, and innate …

Cell therapy with mesenchymal stromal cells (MSCs) is the focus of intensive investigation.
Several clinical trials, including large-scale placebo-controlled phase III clinical trials, are …

Previous studies showed that coculture of primary chondrocytes (PCs) with various sources
of multipotent cells results in a higher relative amount of cartilage matrix formation than …

Background: The three-dimensional (3D) bioprinting technology allows creation of 3D
constructs in a layer-by-layer fashion utilizing biologically relevant materials such as …

Adipose-derived mesenchymal stromal/stem cells (AD-MSC) may offer efficient tools for cell-
based gene therapy approaches. In this study, we evaluated whether AD-MSC could deliver …

Glioblastoma is among the most aggressive and treatment resistant of all human cancers.
Conventional therapeutic approaches are unsuccessful because of diffuse infiltrative …

Osteoprotegerin (OPG) is a glycoprotein involved in the regulation of bone remodelling.
OPG regulates osteoclast activity by blocking the interaction between the receptor activator …

Inducing apoptosis has become an important approach in the development of new anti-
cancer treatments. Tumour necrosis factor apoptosis inducing ligand (TRAIL) based …

Pulmonary arterial hypertension (PAH) is a life-threatening disease characterized by the
progressive narrowing and occlusion of small pulmonary arteries. Current therapies fail to …

The overall aim of this work was to examine the expression profiles for fibroblast growth
factor receptors (FGFRs) and describe their biological importance during bovine pre-and …