Diabetes mellitus (DM) is a chronic metabolic disease characterized by hyperglycaemia that
seriously affects human health. Diabetic cardiomyopathy (DCM) is a major cardiovascular …

Diabetic cardiomyopathy (DCM) is a pathophysiological condition triggered by diabetes
mellitus (DM), which can lead to heart failure (HF). One of the most important cellular …

Background: Inflammatory mediators from macrophages are proven to be involved in
pulmonary vascular remodeling in pulmonary hypertension (PH). Here, this study intends to …

β-cell death contributes to β-cell loss and insulin insufficiency in type 1 diabetes (T1D), and
this β-cell demise has been attributed to apoptosis and necrosis. Apoptosis has been …

Scrophularia ningpoensis Hemsl.(SN) is an herbal medicine used as a functional food in
China. SN has traditionally been used to treat diabetes mellitus (DM), but its mechanism of …

Pyroptosis is a pro-inflammatory form of cell death resulting from the activation of
gasdermins (GSDMs) pore-forming proteins and the release of several pro-inflammatory …

Immune-mediated destruction of the beta-cells in the pancreatic islets of Langerhans is the
underlying cause of type 1 diabetes (T1D). Despite decades of research, the exact …

Objective Asprosin, a recently found adipokine, contributes to β cell dysfunction. Pyroptosis
is a novel programmed cell death form. N6-Methyladenosine (m6A) modification has been …