The role of microRNAs involved in the disorder of blood–brain barrier in the pathogenesis of multiple sclerosis

A Emami Nejad, SM Mostafavi Zadeh… - Frontiers in …, 2023 - frontiersin.org
miRNAs are involved in various vital processes, including cell growth, development,
apoptosis, cellular differentiation, and pathological cellular activities. Circulating miRNAs …

Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of …

MA Erickson, AF Logsdon, EM Rhea… - Brain, behavior, and …, 2023 - Elsevier
COVID-19 and especially Long COVID are associated with severe CNS symptoms and may
place persons at risk to develop long-term cognitive impairments. Here, we show that two …

Immunosuppressive functions of melanoma cell-derived exosomes in plasma of melanoma patients

TL Whiteside - Frontiers in Cell and Developmental Biology, 2023 - frontiersin.org
Tumor-derived exosomes (TEX) are a subset of small extracellular vesicles (sEV) present in
all body fluids of patients with cancer. In plasma of patients with metastatic melanoma …

Evaluating tumor cell-and T cell-derived extracellular vesicles as potential biomarkers of cancer and immune cell competence

TL Whiteside - Expert review of molecular diagnostics, 2023 - Taylor & Francis
ABSTRACT Introduction Extracellular vesicles (EVs) produced by tumors, also called tumor-
derived exosomes (TEX), have been implicated in inducing immune cell suppression in vitro …

Immune capture and protein profiling of small extracellular vesicles from human plasma

Ł Skoczylas, M Gawin, D Fochtman, P Widłak… - …, 2024 - Wiley Online Library
Extracellular vesicles (EVs), the key players in inter‐cellular communication, are produced
by all cell types and are present in all body fluids. Analysis of the proteome content is an …

Tumor-derived Exosomes and Antitumor Immunity

TL Whiteside - The Journal of Immunology, 2024 - journals.aai.org
Cancer immunotherapy, including immune checkpoint blockade, has been approved for
treatment of patients with many cancer types. However, some patients fail to respond to …

[HTML][HTML] The potential of microRNA carried by small extracellular vesicles in cancer plasma to serve as cancer biomarkers

TL Whiteside - Translational Cancer Research, 2023 - ncbi.nlm.nih.gov
1Department of Pathology, University of Pittsburgh School of Medicine and UPMC Hillman
Cancer Center, Pittsburgh, PA, USA; 2Departments of Immunology and Otolaryngology …

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KM Hargadon, M Graner, A Srivastava… - Modulation of T-cell …, 2023 - books.google.com
Extracellular vesicles (EVs) are produced and released by all cells. However, stressed cells,
including cancer cells, produce an excess of EVs, and plasma of cancer patients is enriched …