[HTML][HTML] Towards the sustainable discovery and development of new antibiotics
An ever-increasing demand for novel antimicrobials to treat life-threatening infections
caused by the global spread of multidrug-resistant bacterial pathogens stands in stark …
caused by the global spread of multidrug-resistant bacterial pathogens stands in stark …
[HTML][HTML] Strategic approaches for colon targeted drug delivery: an overview of recent advancements
SH Lee, R Bajracharya, JY Min, JW Han, BJ Park… - Pharmaceutics, 2020 - mdpi.com
Colon targeted drug delivery systems have gained a great deal of attention as potential
carriers for the local treatment of colonic diseases with reduced systemic side effects and …
carriers for the local treatment of colonic diseases with reduced systemic side effects and …
Nanoparticles in nanomedicine: a comprehensive updated review on current status, challenges and emerging opportunities
HM Abdel-Mageed, NZ AbuelEzz… - Journal of …, 2021 - Taylor & Francis
The fast progress in nanomedicine and nanoparticles (NP) materials presents
unconventional solutions which are expected to revolutionise health care with great …
unconventional solutions which are expected to revolutionise health care with great …
Hybrid drugs—a strategy for overcoming anticancer drug resistance?
M Szumilak, A Wiktorowska-Owczarek, A Stanczak - Molecules, 2021 - mdpi.com
Despite enormous progress in the treatment of many malignancies, the development of
cancer resistance is still an important reason for cancer chemotherapy failure. Increasing …
cancer resistance is still an important reason for cancer chemotherapy failure. Increasing …
Advances in colon-targeted nano-drug delivery systems: challenges and solutions
Nano-drug delivery systems (NDDS) for colon-targeted drug delivery are an active area of
research on local diseases affecting the colon, such as ulcerative colitis, Crohn's disease …
research on local diseases affecting the colon, such as ulcerative colitis, Crohn's disease …
[HTML][HTML] Oral delivery of protein and peptide drugs: From non-specific formulation approaches to intestinal cell targeting strategies
G Chen, W Kang, W Li, S Chen, Y Gao - Theranostics, 2022 - ncbi.nlm.nih.gov
The past few years has witnessed a booming market of protein and peptide drugs, owing to
their superior efficiency and biocompatibility. Parenteral route is the most commonly …
their superior efficiency and biocompatibility. Parenteral route is the most commonly …
Formulation strategies for enhancing the bioavailability of silymarin: the state of the art
A Di Costanzo, R Angelico - Molecules, 2019 - mdpi.com
Silymarin, a mixture of flavonolignan and flavonoid polyphenolic compounds extractable
from milk thistle (Silybum marianum) seeds, has anti-oxidant, anti-inflammatory, anti-cancer …
from milk thistle (Silybum marianum) seeds, has anti-oxidant, anti-inflammatory, anti-cancer …
[HTML][HTML] Recent advancements in non-invasive formulations for protein drug delivery
R Bajracharya, JG Song, SY Back, HK Han - Computational and structural …, 2019 - Elsevier
Advancements in biotechnology and protein engineering expand the availability of various
therapeutic proteins including vaccines, antibodies, hormones, and growth factors. In …
therapeutic proteins including vaccines, antibodies, hormones, and growth factors. In …
Therapeutic targeting of the oncogenic Wnt signaling pathway for treating colorectal cancer and other colonic disorders
M Caspi, A Wittenstein, M Kazelnik… - Advanced drug delivery …, 2021 - Elsevier
The canonical Wnt pathway is one of the key cellular signaling cascades that regulates, via
the transcriptional co-activator β-catenin, numerous embryogenic developmental processes …
the transcriptional co-activator β-catenin, numerous embryogenic developmental processes …
[HTML][HTML] Sustained and targeted delivery of hydrophilic drug compounds: A review of existing and novel technologies from bench to bedside
D Hawthorne, A Pannala, S Sandeman… - Journal of Drug Delivery …, 2022 - Elsevier
The sustained and/or targeted delivery of hydrophilic drugs is an important field within drug
delivery, presenting unique challenges when compared to that of hydrophobic drugs. Yet …
delivery, presenting unique challenges when compared to that of hydrophobic drugs. Yet …